{"id":14103,"date":"2018-01-02T16:04:56","date_gmt":"2018-01-02T16:04:56","guid":{"rendered":"http:\/\/i-base.info\/qa\/?p=14103"},"modified":"2018-01-02T16:04:56","modified_gmt":"2018-01-02T16:04:56","slug":"could-hiv-drugs-be-an-annual-implant","status":"publish","type":"post","link":"https:\/\/i-base.info\/qa\/14103","title":{"rendered":"Could HIV drugs be an annual implant?"},"content":{"rendered":"<p>Hi<\/p>\n<p>You are right that one compound in development might be available as a slow release implant.<\/p>\n<p>The compound is called EFdA and we reported early studies presented at a conference last year. It is also now called MK-8591.<br \/>\n<a href=\"https:\/\/i-base.info\/htb\/29774\">https:\/\/i-base.info\/htb\/29774<\/a><\/p>\n<p>Although an annual implant might be available for this drug, HIV treatment usually needs three drugs in a combination, or sometimes only two. Either way, EFdA will need to be used in combination with other long-activing molecules and currently there are no-other long acting drugs to use with it.<\/p>\n<p>The research into the annual implant therefore is for use by HIV negative people as PrEP &#8211; i.e. to prevent infection.<\/p>\n<p>If one drug can be produced with this profile, there is hope that another might be discovered, just that none are available yet.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hi\u00a0<\/p>\n<p>Is there any research on a long term medical implant going on ?<\/p>\n<p>I read somewhere a bio degradable implant is being worked on which will last one year. This would effectively be a cure I would think as It would only require yearly or six monthly doctor visits.\u00a0Surely this would be more cost effective than daily pills ?<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7,53],"tags":[],"class_list":["post-14103","post","type-post","status-publish","format-standard","hentry","category-all-topics","category-research"],"_links":{"self":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/14103","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/comments?post=14103"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/14103\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/media?parent=14103"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/categories?post=14103"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/tags?post=14103"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}