{"id":17298,"date":"2021-06-30T10:36:12","date_gmt":"2021-06-30T10:36:12","guid":{"rendered":"https:\/\/i-base.info\/qa\/?p=17298"},"modified":"2021-06-30T10:36:12","modified_gmt":"2021-06-30T10:36:12","slug":"can-on-demand-211-prep-be-used-by-straight-men-or-women","status":"publish","type":"post","link":"https:\/\/i-base.info\/qa\/17298","title":{"rendered":"Can on-demand (2:1:1) PrEP be used by straight men? or women?"},"content":{"rendered":"<p>Hi<\/p>\n<p>Thanks for your questions.<\/p>\n<p>On demand dosing depends on which part of your body will come into contact with HIV.<\/p>\n<p>The main difference is that PrEP drugs reach much higher levels in anal tissue compared to vaginal tissue.<\/p>\n<p>So if your <strong>only<\/strong> risk is from anal sex and you are being fucked, on demand dosing can be used by everyone.<\/p>\n<p>Any risk from vaginal (or front hole) sex and you are being fucked, needs daily dosing.<\/p>\n<p>In practice, this mean most cis gender and trans gender women use daily dosing.<\/p>\n<p>Trans gender men who have front hole sex also need to use daily dosing.<\/p>\n<p>Cis gender men can use on demand for any type of sex. It doesn&#8217;t matter whether you are gay or straight.<\/p>\n<p>This is because the IPERGAY study reported no infections in men who risk was just from insertive sex (ie being active for anal sex).<\/p>\n<p><strong>More info on PrEP dosing<\/strong><\/p>\n<ul>\n<li><a href=\"https:\/\/i-base.info\/guides\/prep\/daily-prep-for-anal-and-vaginal-sex\">Daily PrEP: for anal and vaginal sex<\/a><\/li>\n<li><a href=\"https:\/\/i-base.info\/guides\/prep\/on-demand\">On-demand dosing: for anal sex or straight men having vaginal sex <\/a><\/li>\n<li><a href=\"https:\/\/i-base.info\/guides\/prep\/real-life-examples-for-on-demand-dosing\">Real-life examples for on-demand dosing<\/a><\/li>\n<\/ul>\n<p><strong>UK guide to PrEP<\/strong><\/p>\n<ul>\n<li><a href=\"https:\/\/i-base.info\/guides\/prep\">UK guide to PrEP<\/a><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Hi. <\/p>\n<p>Is on demand prep just for anal &#8211; or also straight men having virginal sex? Is it only for men or both genders?<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7,51],"tags":[],"class_list":["post-17298","post","type-post","status-publish","format-standard","hentry","category-all-topics","category-prep"],"_links":{"self":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/17298","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/comments?post=17298"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/17298\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/media?parent=17298"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/categories?post=17298"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/tags?post=17298"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}