{"id":20010,"date":"2022-06-22T16:53:13","date_gmt":"2022-06-22T16:53:13","guid":{"rendered":"https:\/\/i-base.info\/qa\/?p=20010"},"modified":"2024-08-26T14:40:58","modified_gmt":"2024-08-26T14:40:58","slug":"will-pep-work-if-it-was-in-below-0-degrees-temperature","status":"publish","type":"post","link":"https:\/\/i-base.info\/qa\/20010","title":{"rendered":"Will PEP work if it was in below 0 degrees temperature?"},"content":{"rendered":"<p>Hi, how are you?<\/p>\n<p>You have mentioned that you did not take PEP for 2 months. Does this mean you waited 2 months after exposure before starting PEP? PEP needs to be started within 72 hours of the exposure. At 2 months PEP would no longer be effective and you would need to test to confirm your status.<\/p>\n<p>A lot of medication have requirements to be kept below 25 degrees. This is to stop temperature breaking the medication down. PEP being in very cold temperatures for a short while is not going to effect how well it works. It is also likely the medication was not this cold if it was in your pocket or something similar.<\/p>\n<p>Please see this link for more information about PEP:<br \/>\n<a style=\"font-size: 16px; font-variant-caps: normal;\" href=\"https:\/\/i-base.info\/qa\/factsheets\/pep-faq\" rel=\"noopener\" data-saferedirecturl=\"https:\/\/www.google.com\/url?q=https:\/\/i-base.info\/qa\/factsheets\/pep-faq&amp;source=gmail&amp;ust=1724092211850000&amp;usg=AOvVaw3MtZP4p_TZNLaWKIRsumit\">https:\/\/i-base.info\/qa\/<wbr \/>factsheets\/pep-faq<\/a><\/p>\n<p>Josh.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hello! I had sexual intercourse. For fear of HIV, I went to the hospital and got PEP. PEP is a post-exposure prophylaxis which I adopt to prevent HIV after exposure. It is taken for 28 days, but I was afraid to take it for two months. The fear was that I was outside for several hours, with a temperature of minus 2 degrees. On drugs it says to store at a temperature of 25 degrees. The drugs are emtricitabine \/ tenofovir, darunavir and ritonavir. Could 4 hours at minus 2 degrees C make these drugs effective?<\/p>\n","protected":false},"author":18,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4,7,31],"tags":[],"class_list":["post-20010","post","type-post","status-publish","format-standard","hentry","category-access-to-treatment","category-all-topics","category-peppepse"],"_links":{"self":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/20010","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/users\/18"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/comments?post=20010"}],"version-history":[{"count":1,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/20010\/revisions"}],"predecessor-version":[{"id":23890,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/20010\/revisions\/23890"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/media?parent=20010"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/categories?post=20010"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/tags?post=20010"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}