Hi, how are you doing?<\/p>\n
In most cases it is fine to do this once e.g., complete the first regimen of on-demand dosing using a double dose, then restarting with a single dose within 7 days.<\/p>\n
However this is usually on suggested as a one-off thing and not to be repeated.<\/p>\n
Doing this regularly on a 1-1-1 dose means you are only using PrEP 3\/7 days on a single dose. Not suing that initial double dose can reduce the required initial level of PrEP in your body – this is accounted for by repeating the regimen once.<\/p>\n
For this reason it would either be recommended to always use a double dose on the Friday if you want to continue on-demand, or move to a daily regimen and build PrEP into your daily routine.<\/p>\n
Josh.<\/p>\n","protected":false},"excerpt":{"rendered":"
Weekly on-demand PrEP dosing?<\/p>\n
I tend to have sex on Fridays nights. Is a double dose required when restarting on-demand PrEP on Friday mornings when the last previous dose was on Sunday?<\/p>\n
Different pages on your website say different things about gaps of less than 7 days. Obviously a 2-1-1 pattern is needed for gaps of longer than a week, but it is unclear whether 1-1-1 is possible if taken weekly.<\/p>\n","protected":false},"author":18,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,7,51],"tags":[],"class_list":["post-22125","post","type-post","status-publish","format-standard","hentry","category-adherence","category-all-topics","category-prep"],"_links":{"self":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/22125","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/users\/18"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/comments?post=22125"}],"version-history":[{"count":1,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/22125\/revisions"}],"predecessor-version":[{"id":22126,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/22125\/revisions\/22126"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/media?parent=22125"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/categories?post=22125"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/tags?post=22125"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}