{"id":23102,"date":"2024-04-10T15:28:11","date_gmt":"2024-04-10T15:28:11","guid":{"rendered":"https:\/\/i-base.info\/qa\/?p=23102"},"modified":"2024-08-17T04:48:59","modified_gmt":"2024-08-17T04:48:59","slug":"what-if-pep-includes-atazanavir-and-i-also-take-omeprazole","status":"publish","type":"post","link":"https:\/\/i-base.info\/qa\/23102","title":{"rendered":"What if PEP includes atazanavir and I also take omeprazole?"},"content":{"rendered":"<p>Hi there<\/p>\n<p>Thanks, please tell the doctor that prescribed PEP that you also take omeprazole.<\/p>\n<p>This is because omeprazole can significantly reduce levels of atazanavir so it would not be working as PEP.<\/p>\n<p>Please see this link:<a href=\"https:\/\/www.hiv-druginteractions.org\/downloads\/ajd45jg-4er5-67oy-ur43-009ert.pdf?interaction_ids%5B%5D=102922&amp;interaction_ids%5B%5D=103633\" rel=\"noopener\"><br \/>\nSummary of drug interaction between atazanaivr and omeprazole.<\/a><\/p>\n<p>You could also talk to a pharmacist for alternative antacids that do not have this interaction. As PEP is only for 28 days, using an alternative might be easier that getting different PEP.<\/p>\n<p>Otherwise, separating PEP from omeprazole by 12 hours might be okay, but your doctor needs to know about this.<\/p>\n<p>Information about PEP, including the different drugs is at this link:<br \/>\n<a href=\"https:\/\/i-base.info\/qa\/factsheets\/pep-faq\">https:\/\/i-base.info\/qa\/factsheets\/pep-faq<\/a><\/p>\n\n","protected":false},"excerpt":{"rendered":"<p>Hi. I just started PEP two days ago. They gave me a combination of Truvada and Atazor.<\/p>\n<p>The side effects I\u2019m experiencing the most are stomach ache, nausea and diarrhoea. Can I control those with prescriptions? If yes, which ones do you recommend and how much time apart from the PEP medications.<\/p>\n<p>I read online that omeprazole interacts with atazanavir, substantially decreasing its levels in the blood, and Ioperamide interacts with atazanavir and can lead to irregular heart rhythm and cardiac arrest.<\/p>\n<p>I typically use omeprazole for stomach ache and loperamide for diarrhoea, so I&#8217;m having a hard time finding a prescription that can help control my symptoms but and the same time don&#8217;t interact with atazor.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7,16,31],"tags":[],"class_list":["post-23102","post","type-post","status-publish","format-standard","hentry","category-all-topics","category-drug-interactions","category-peppepse"],"_links":{"self":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/23102","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/comments?post=23102"}],"version-history":[{"count":8,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/23102\/revisions"}],"predecessor-version":[{"id":23224,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/23102\/revisions\/23224"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/media?parent=23102"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/categories?post=23102"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/tags?post=23102"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}