{"id":26805,"date":"2026-09-29T12:25:03","date_gmt":"2026-09-29T12:25:03","guid":{"rendered":"https:\/\/i-base.info\/qa\/?p=26805"},"modified":"2026-09-29T12:25:03","modified_gmt":"2026-09-29T12:25:03","slug":"is-there-a-way-to-remove-long-acting-hiv-drugs-in-case-there-are-side-effects","status":"publish","type":"post","link":"https:\/\/i-base.info\/qa\/26805","title":{"rendered":"Is there a way to remove long-acting HIV drugs in case there are side effects?"},"content":{"rendered":"<p>Hi there<\/p>\n<p>Thanks, this is a great question.<\/p>\n<p>Although most people use oral HIV meds, some people can use injectable ART.<\/p>\n<p>This mainly involves long-acting <a href=\"https:\/\/i-base.info\/guides\/15361\">cabotegravir (CAB-LA<\/a>) and long-acting <a href=\"https:\/\/i-base.info\/guides\/15361\">rilpivirine (RPV-LA).<\/a><\/p>\n<p>Other injectable HIV meds include <a href=\"https:\/\/i-base.info\/guides\/15358\">lenacapavir (LEN)<\/a> and <a href=\"https:\/\/i-base.info\/guides\/14466\">ibalizumab,<\/a> although thes are used in combiantions when there is resistance to oral meds.<\/p>\n<p>The advantages of long-acting meds include less frequent dosing it means the drugs stay in your body for a long time, which could be a problem if you have a bad reaction.<\/p>\n<p>Luckily, these meds are generally well tolerated and most side effects are linked to having the injections.<\/p>\n<p>The longest acting meds &#8211; CAB\/RPV is given every two months and LEN is given every 6 months &#8211; also involve starting with oral dosing. This is to quickly reach the right drug levels but it also has a safety role is checking that there are no serious allergic reactions to the active drugs,<\/p>\n<p>So although there are not antidotes that can quickly remove long-acting drugs, the short time taking oral drugs is a good indication \u00a0that there will not be allergic reactions.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hi there, I am thinking about whether injectable ART would be better for me and one of the things I worry about is what happends if I get side effects? Are there antidotes that would clear these drugs from my body if I have a bad reaction?<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,7,10,57,38],"tags":[],"class_list":["post-26805","post","type-post","status-publish","format-standard","hentry","category-adherence","category-all-topics","category-changing-treatment","category-injectable-art","category-side-effects"],"_links":{"self":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/26805","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/comments?post=26805"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/26805\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/media?parent=26805"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/categories?post=26805"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/tags?post=26805"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}