{"id":429,"date":"2008-05-06T17:59:06","date_gmt":"2008-05-06T16:59:06","guid":{"rendered":"http:\/\/www.i-base.info\/qa\/?p=429"},"modified":"2021-11-22T12:18:28","modified_gmt":"2021-11-22T12:18:28","slug":"is-it-safe-to-take-st-johns-wort-while-on-antiretrovirals","status":"publish","type":"post","link":"https:\/\/i-base.info\/qa\/429","title":{"rendered":"Is it safe to take St. John&#039;s wort while on antiretrovirals?"},"content":{"rendered":"<p>Thank you for your question. St. John&#8217;s wort is effective in treating mild to moderate depression with little or no side effects. But a very small percentage of people experience side-effects such as fatigue, restlessness, sensitivity to heat or cold, a rash and nausea.<\/p>\n<p>St. John&#8217;s wort is not recommended when you are taking non-nucleoside reverse transcriptase inhibitors (NNRTIs) or protease inhibitors (PIs). It reduces the levels of these drugs which may put someone on these drugs at risk of resistance and eventually treatment failure.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>I am on Kivexa and Atanazavir. I would like to know if it is safe to take St. John&#8217;s wort with my antiretrovirals?<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7,16,35,38,40],"tags":[],"class_list":["post-429","post","type-post","status-publish","format-standard","hentry","category-all-topics","category-drug-interactions","category-resistance","category-side-effects","category-supplements-and-herbs"],"_links":{"self":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/429","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/comments?post=429"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/429\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/media?parent=429"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/categories?post=429"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/tags?post=429"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}