{"id":4358,"date":"2011-07-07T06:47:15","date_gmt":"2011-07-07T06:47:15","guid":{"rendered":"http:\/\/i-base.info\/qa\/?p=4358"},"modified":"2011-07-07T06:47:15","modified_gmt":"2011-07-07T06:47:15","slug":"4358","status":"publish","type":"post","link":"https:\/\/i-base.info\/qa\/4358","title":{"rendered":"What can I do to reduce my viral load that rebounded on Kaletra?"},"content":{"rendered":"<p>If Kaletra was the only HIV drug that you were taking, adding in two new drugs from a family called nucleosides (&#8216;nukes&#8217;) should bring your viral load back down again.<\/p>\n<p>Although most combinations use three active HIV drugs, several studies showed that for some people, using only Kaletra is strong enough. In these studies, when viral load rebounded, adding in new drugs worked well at pushing the viral load back down again.<\/p>\n<p>If you have been taking Kaletra once-daily (4 tablets once-daily), then your doctor may also recommend moving to a twice-daily schedule (2 tablets, twice daily &#8211; every 12 hours).<\/p>\n<p>The new drugs would usually be adding Truvada (tenofovir\/FTC) or Kivexa (abacavir\/3TC) or sometimes Combivir (AZT\/3TC).<\/p>\n<p>However, if you have resistance to Kaletra, then this would normally need to be changed at the same time to an alternative protease inhibitor.<\/p>\n<p>For more information about treatment failure and drug resistance see the <a href=\"https:\/\/i-base.info\/guides\/\">Guide to Changing Treatment<\/a>.<\/p>\n<p>This is all down to find drugs that will control the virus. Other than taking your meds as prescribed, there is nothing else you can do to directly affect viral load.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>I&#8217;ve recently had my bloods done and my viral load has gone up to 1,563.<\/p>\n<p>I&#8217;m currently on Kaletra  and have been taking them everyday as told but know my doctor is telling me i have to go on more tablets as im showing resistance.<\/p>\n<p>Is there anything else i can do to improve my viral load aswell as taking the medication?<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7,9,10],"tags":[],"class_list":["post-4358","post","type-post","status-publish","format-standard","hentry","category-all-topics","category-cd4-and-viral-load","category-changing-treatment"],"_links":{"self":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/4358","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/comments?post=4358"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/4358\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/media?parent=4358"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/categories?post=4358"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/tags?post=4358"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}