I can understand that it can be difficult at times, especially at work, to follow and maintain a routine.\u00a0 Taking medication everyday and on time is very important\u00a0 because the drugs has to be kept at enough level to keep HIV under control, all of the time.\u00a0 Missing or late dosage means you will not absorb enough of the drugs for it to work properly and you can develop resistance.<\/p>\n
There is usually a window period of about 1 or 2 hour that is still okay and all combination drugs are flexible enough to allow this widow period.\u00a0 The odd occasion of missing or being late with a dose (say once a month) may not make very much difference but do make sure it does not become too regular.<\/p>\n
If your viral load is currently undetectable and has been this low for more than 6 months, the combination of efavirenz and truvada probably had sufficient flexibility for you to sometimes be up to four hours late with the efavirenz.<\/p>\n
The two drugs in truvada will cover any short period when efavirenz levels are low, but efavirenz all is pretty good at having a buffer level at the end of each dose, so should hopefully not drop this low anyway.<\/p>\n
The best way to avoid resistance is to take all your medications on time, everyday and also to follow any diet restriction (for example with or without food).\u00a0 One suggestion is for you to have a bleeper\/timer with you all the time or perhaps you could ask one of your close friend or a family member to also remind you.<\/p>\n