{"id":551,"date":"2008-08-21T16:19:39","date_gmt":"2008-08-21T15:19:39","guid":{"rendered":"http:\/\/www.i-base.info\/qa\/?p=551"},"modified":"2021-11-22T12:18:20","modified_gmt":"2021-11-22T12:18:20","slug":"are-my-results-going-the-wrong-way","status":"publish","type":"post","link":"https:\/\/i-base.info\/qa\/551","title":{"rendered":"Are my results going the wrong way?"},"content":{"rendered":"<p>Thanks for your questions. I&#8217;ll try to answer them following your numbering:<\/p>\n<p>1. The test results<\/p>\n","protected":false},"excerpt":{"rendered":"<p>I was negative in December 2007 and contracted genital HSV1 infection in March 2008. I had an episode of primary HSV infection which took 2 weeks to settle and was associated with anal lesions, swollen lymph nodes in neck and groin, fever and general body ache.<\/p>\n<p>I went for a complete STD panel and was diagnosed with HSV 1 and HIV 1 (Subtype B) on 02 April 2008. Since then I have also had anal warts and suspect HPV infection as well. I have had a very low risk history with use of condoms for anal sex. My doctor says that I have been unlucky to have it through oral sex.<\/p>\n<p>I have had three sets of ELISA and WB tests on different samples on different days but same laboratory and they all are positive.<\/p>\n<p>My baseline CD4 was 819\/CD4% 20\/ VL 27330 in March 2008. I repeated my tests in June 2008 and the results were CD4 642\/CD4% 22\/ VL 108000.<\/p>\n<p>Resistance testing has shown no resistance.<\/p>\n<p>I now present my questions<\/p>\n<p>1. How reliable is the HIV diagnosis in view of a simultaneous HSV 1 and HPV Infection? Is there a probability of any cross reaction? I ask this because I have always been low risk and did not have any symptoms of seroconversion between my negative test in December 2007 and 23 March 2008 (when I got HSV).<\/p>\n<p>2. My results seem to be going the wrong way. As you can see my VL has gone up 400 % and my CD4 count has reduced by 22 % but my CD4% has improved by 2%. This appears to be a huge drop in CD4 and a massive increase in VL. I am extremely worried by such deterioration in results in just 3 months, considering the fact that I was negative in December 2007. Could you please comment on my results and what they mean?<\/p>\n<p>3. Can HBV vaccination, which I have received twice in the last 3 months, cause of high viral load?<\/p>\n<p>4. What implication HSV1 and HPV co infection has on HIV VL? Is this a possible cause of my high VL? My doctor is not concerned about the results and in his opinion these are just the same results.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7,9,30],"tags":[],"class_list":["post-551","post","type-post","status-publish","format-standard","hentry","category-all-topics","category-cd4-and-viral-load","category-other-tests"],"_links":{"self":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/551","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/comments?post=551"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/551\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/media?parent=551"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/categories?post=551"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/tags?post=551"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}