{"id":5749,"date":"2023-01-24T12:10:32","date_gmt":"2023-01-24T12:10:32","guid":{"rendered":"http:\/\/i-base.info\/qa\/?p=5749"},"modified":"2023-07-06T22:44:13","modified_gmt":"2023-07-06T22:44:13","slug":"should-i-continue-taking-septrin-if-my-cd4-count-has-risen-to-above-200","status":"publish","type":"post","link":"https:\/\/i-base.info\/qa\/5749","title":{"rendered":"Should I continue taking septrin if my CD4 count  has risen to above 200?"},"content":{"rendered":"<p>It is really good news that your CD4 count has risen to 270 cells from such a low count.<\/p>\n<p>Septrin is prescribed as prophylaxis against PCP [a type of pneumonia] when someone has a CD4 count of below 200 cells, and against toxoplasmosis (a type of brain infection) someone is at risk of developing with a CD4 count of less than 100 cells.<\/p>\n<p>In the UK, once a person\u2019s CD4 count increases to above 100 cells when on treatment, then they can stop Septrin. That is, unless they have previously had PCP.<\/p>\n<p>For someone who has previously had PCP, it is recommended to continue until the CD4 count is above 200 cells\/mm<sup>3<\/sup>. This is based on EACS guidelines (v11.1, October 2022).<\/p>\n<p>In some African countries, Septrin is recommended until the CD4 count is over 350 (and sometimes until over 500). This is because the background risk of infections can vary in different countries.<\/p>\n<p>In countries with high risk of malaria or severe bacterial infections, prophylaxis should continue, irrespective of CD4 count on ART. There are also different recommendations for children and in other specific circumstances. (WHO consolidated guidelines, 2021)<\/p>\n<p>In terms of safety, if your doctor has recommended that you continue taking the septrin, then this is very safe to do so.<\/p>\n<p><em>This pot was updated in January 2023 from a question frost answered in January 2012.\u00a0<\/em><\/p>\n<p><!--EndFragment--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>How long can a person take Septrin?<\/p>\n<p>Is it ok to continue taking it even if CD4 levels have risen (from below 10 to 270)?<br \/>\nThanks.<\/p>\n","protected":false},"author":9,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7,29],"tags":[],"class_list":["post-5749","post","type-post","status-publish","format-standard","hentry","category-all-topics","category-opportunistic-infections"],"_links":{"self":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/5749","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/comments?post=5749"}],"version-history":[{"count":7,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/5749\/revisions"}],"predecessor-version":[{"id":22081,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/5749\/revisions\/22081"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/media?parent=5749"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/categories?post=5749"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/tags?post=5749"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}