{"id":6345,"date":"2012-03-16T15:57:30","date_gmt":"2012-03-16T15:57:30","guid":{"rendered":"http:\/\/i-base.info\/qa\/?p=6345"},"modified":"2016-08-31T22:46:54","modified_gmt":"2016-08-31T22:46:54","slug":"is-a-fast-heartbeat-on-atripla-normal","status":"publish","type":"post","link":"https:\/\/i-base.info\/qa\/6345","title":{"rendered":"Is a fast heartbeat on Atripla normal?"},"content":{"rendered":"<p>As with any symptoms, this is something to call your doctor about. This is especially important if you think there is a change in your heart beat or heart rhythm.\u00a0Your doctor can then run tests to check whether you are ok.<\/p>\n<p>The three drugs in Atripla are efavirenz, tenofovir and FTC. These drugs have not been associated with these symptoms.<\/p>\n<p>I also wondered what you meant by bad adherence? How often are you late or do you sometimes miss doses completely?<\/p>\n<p>Because the three drugs in Atripla leave your body quite slowly compared to some other HIV drugs, you may have a bigger window to take them. This means that even being several hours late may be fine, so long as you still take one tablet a day.<\/p>\n<p>If you get your viral load to undetectable and keep it there for at least six months, you may have even more flexibility.<\/p>\n<p>A <a href=\"http:\/\/library.iasociety.org\/AbstractView.aspx?confID=2009&amp;abstractId=3046\">study called FOTO (Five On, Two On)<\/a> followed people with an undetectable viral for a year when they only took Atripla from Monday to Friday (Five On) and didn&#8217;t take it at weekends (Two Off). In this study, viral load stayed undetectable all year.<\/p>\n<p>This schedule is not approved or recommended but it shows that evens missing a day or two sometimes may be fine, but only if your viral load is undetectable. This may take some of the stress away from your worrying about bad adherence.<\/p>\n<p>Again though, talk to your doctor about this as they will have the time to take in detail about other things that could help.<\/p>\n<p>Reference:<\/p>\n<p>Cohen C et al. The FOTO study: The 48 week extension to assess durability of the strategy of taking efavirenz, tenofovir and emtricitabine Five days On, Two days Off (FOTO) each week in virologically suppressed patients. 5th IAS Conference, 2009. Abstract MOPEB063.<br \/>\n<a href=\"http:\/\/library.iasociety.org\/AbstractView.aspx?confID=2009&amp;abstractId=3046\">http:\/\/library.iasociety.org\/AbstractView.aspx?confID=2009&amp;abstractId=3046<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>On Atripla for the past 12 months, in the last 1-2 months I have fast heart beat. is this normal? I like the idea of having one tablet daily as my adherance is bad.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,7,38],"tags":[],"class_list":["post-6345","post","type-post","status-publish","format-standard","hentry","category-adherence","category-all-topics","category-side-effects"],"_links":{"self":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/6345","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/comments?post=6345"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/posts\/6345\/revisions"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/media?parent=6345"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/categories?post=6345"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/i-base.info\/qa\/wp-json\/wp\/v2\/tags?post=6345"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}