{"id":1345,"date":"2023-01-01T12:00:41","date_gmt":"2023-01-01T12:00:41","guid":{"rendered":"http:\/\/i-base.info\/ttfa\/?page_id=1345"},"modified":"2024-07-13T08:52:06","modified_gmt":"2024-07-13T08:52:06","slug":"appendix-7-ias-usa-resistance-mutations-and-cross-resistance","status":"publish","type":"page","link":"https:\/\/i-base.info\/ttfa\/hiv-and-drug-resistance\/appendix-7-ias-usa-resistance-mutations-and-cross-resistance\/","title":{"rendered":"9.  Appendix 7: IAS-USA resistance mutations and cross-resistance"},"content":{"rendered":"<p>The following figures from the International Antiviral Society USA (IAS-USA) show mutations for each drug and cross-resistance between drugs in each class.<\/p>\n<p>The <a href=\"https:\/\/www.iasusa.org\/resources\/hiv-drug-resistance-mutations\/\" rel=\"noopener\">IAS-USA website<\/a> includes free download of the latest guidelines to HIV drug resistance published in 2022 in Topics in HIV Medicine. This is the source for the the following tables. <a href=\"https:\/\/iasusa.wpenginepowered.com\/wp-content\/uploads\/2022\/10\/30-4-559.pdf\" target=\"_blank\" rel=\"noopener\">https:\/\/www.iasusa.org\/sites\/default\/files\/tam\/21-1-6.pdf<\/a> (PDF)<\/p>\n<p>Please check the IAS-USA site for updates to these resources. Please refer to the full guidelines for the notes and references. The information on new mutations and how to interpret them is regularly updated, especially for latest drugs.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-10867 aligncenter\" src=\"https:\/\/i-base.info\/wp-content\/uploads\/2014\/05\/IAS-USA-key-2013.png\" alt=\"IAS-USA key 2013\" width=\"454\" height=\"133\" \/><\/p>\n\n\n<p>The table below shows the table tor NRTIs and is included as an example.<\/p>\n<p>Please use the above links to see similar tables for other types of HIV drugs: NNRTIs, PIs, integrase inhibitors etc.<\/p>\n\n\n\n<p><a href=\"https:\/\/i-base.info\/ttfa\/wp-content\/uploads\/2023\/01\/IAS-NRTI-table.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-1883 size-full\" src=\"https:\/\/i-base.info\/ttfa\/wp-content\/uploads\/2023\/01\/IAS-NRTI-table.png\" alt=\"\" width=\"1549\" height=\"1067\" srcset=\"https:\/\/i-base.info\/ttfa\/wp-content\/uploads\/2023\/01\/IAS-NRTI-table.png 1549w, https:\/\/i-base.info\/ttfa\/wp-content\/uploads\/2023\/01\/IAS-NRTI-table-300x207.png 300w, https:\/\/i-base.info\/ttfa\/wp-content\/uploads\/2023\/01\/IAS-NRTI-table-1024x705.png 1024w, https:\/\/i-base.info\/ttfa\/wp-content\/uploads\/2023\/01\/IAS-NRTI-table-768x529.png 768w, https:\/\/i-base.info\/ttfa\/wp-content\/uploads\/2023\/01\/IAS-NRTI-table-1536x1058.png 1536w\" sizes=\"auto, (max-width: 1549px) 100vw, 1549px\" \/><\/a><\/p>\n\n\n\n\n\n\n\n\n\n","protected":false},"excerpt":{"rendered":"<p>The following figures from the International Antiviral Society USA (IAS-USA) show mutations for each drug and cross-resistance between drugs in each class. The IAS-USA website includes free download of the latest guidelines to HIV drug resistance published in 2022 in &hellip;<\/p>\n","protected":false},"author":5,"featured_media":0,"parent":1277,"menu_order":12,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1345","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/i-base.info\/ttfa\/wp-json\/wp\/v2\/pages\/1345","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/i-base.info\/ttfa\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/i-base.info\/ttfa\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/i-base.info\/ttfa\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/i-base.info\/ttfa\/wp-json\/wp\/v2\/comments?post=1345"}],"version-history":[{"count":0,"href":"https:\/\/i-base.info\/ttfa\/wp-json\/wp\/v2\/pages\/1345\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/i-base.info\/ttfa\/wp-json\/wp\/v2\/pages\/1277"}],"wp:attachment":[{"href":"https:\/\/i-base.info\/ttfa\/wp-json\/wp\/v2\/media?parent=1345"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}