On-demand dosing – a term for taking medicines only at times linked to a relevant event.
On-demand dosing for PrEP is also called “event based dosing” (EBD).
For example, on-demand dosing for PrEP (to prevent HIV transmission) involves taking PrEP before sex and then for several days after sex. EBD for PrEP is only appropriate in some situations and for some people – otherwise daily dosing is recommended,
lipoatrophy – fat loss in your arms, legs or face. Lipoatrophy is a type of lipodystrophy.
viral tropism see tropism.
half-life (T1/2) – the time taken a drug to clear from the highest concentration to half this level. Drugs have different half-lives in different compartments (ie half-life in blood can be different from the half-life inside a cell). It take 5 x the half-live for a drug to be considered cleared.
epoetin-alpha (EPO) – a treatment for anaemia, given by injection. Used to reduce side effect of hepatitis C treatment.