HIV i-Base

DAA (direct acting antiviral)

DAA (direct acting antiviral) – new hepatitis C drugs that work directly against the hepatitis C virus (HCV).

Since 2014, the following DAAs and fixed dose combinations have been approved – and more are in development. Links are to the EMA website for information on each DAA.

Previously, HCV was treated with pegylated interferon (PEG-IFN) plus ribavirin (RBV).

Even though HCV guidelines now only recommend oral DAA treatment, the high price of these medicines means that in many countries they are only available to people who have advanced liver damage.