HIV i-Base

Selected words and phrases

salvage therapy – a term for the combination therapy used after someone has developed resistance to three or more classes of HIV drugs. Also called ‘third-line’ or ‘rescue therapy’ or ‘treatment of patients with multidrug resistance’.

toxicity – medical word for side effect, the potential harm a drug can cause.

formulation – the physical form that makes an active drug into a medicine.

Different formulations include

  • Pills (capsules or tablets).
  • Syrups or other oral solutions.
  • Injections.
  • Powders.
  • Creams or lotions.

A co-formulation is when two active drugs are combined. For example: when two active drugs are in the same pill.

resistance tests – tests to show changes to HIV that are associated with drug resistance. Genotype resistance test looks for genetic changes. Phenotype resistance test see whether individual drugs are still active when placed in a test tube with HIV.

Resistance tests.