HIV i-Base

Selected words and phrases

stage (staging) – the stage of hepatitis infection refers to the amount of scaring (fibrosis), from results from a biposy. It is usually measured on the Metavir scale of 0 to 4, where 0 represents no scarring and 4 cirrhosis, or on the Knodell scale of 0 to 6, where 0 is no scarring and 6 cirrhosis. See grading.

tropism – the type of coreceptor used by HIV in order to attach to and then infect a cell. If HIV uses the CCR5 coreceptor on the surface of the a CD4 cell it is called R5-tropic. If it uses the CXCR4 co receptor it is called R4-tropic). Early HIV infection is usually R5-tropic but over time, especially in late disease (if CD4 counts drop to less than 50 cells/mm3) the virus shifts to being X4-tropic.  Mixed tropic refers to a having some viruses that use R5 and some that use X4.

thrombocytopenia – a low platelet count (platelets help stop bleeding by clotting blood).

partially active – the HIV treatment in question will work against this virus but this is reduced compared to wild-type HIV. This is the same as partial resistance, or intermediate resistance etc.