HIV i-Base

Selected words and phrases

Hickman line – a fixed central line that is used to deliver IV drugs close to where they are needed in the body.

CSF – cerebral spinal fluid – the fluid that circulates around the brain and spinal column.

compensatory mutation – this refer to an additional mutation, usually in the context of the fitness of a virus. For example, the mutations that stop a drug form working often stop the virus from reproducing as well. Additional mutations that return the virus to it’s former fitness are called compensatory mutations. They compensate for the reduced viral fitness. See revertant mutation.