HIV i-Base

Selected words and phrases

anaemia – shortage of oxygen-carrying red blood cells

DNA – an abbreviation for the scientific word for genes and genetic material. It is the abbreviation for deoxyribonucleic acid. See RNA.

study population - the group of people in a study.

PI (protease inhibitor) – a type of HIV drug. Protease inhibitors are in development for hepatitis C. HIV protease inhibitors include atazanavir, darunavir, fosamprenavir, indinavir, nelfinavir, lopinavir/r (Kaletra), ritonavir, saquinavir and tipranavir.

Drug targets in the virus life cycle

natural history – the pattern a disease follows if it is not treated. The natural history of HIV includes very high viral load in the first weeks or months of infection (seroconversion), a drop in CD4 counts that then recovers, and then a slower progressive increase in viral load and decrease in CD4 count, that eventually lead to opportunistic infections.

Natural history graph and more details.