Glossary

lactic acidosis – dangerous build up of lactate in the blood.

ETR (end of treatment response) – having an undetectable HCV viral load at the end of HCV treatment. See SVR.

haematology – study (-ology) of blood (haema-)

wasting – loss of lean body mass (muscle loss). A unplanned or unexplained wight loss of more than 5% body weight over six months can be an AIDS-defining illness.

Weight loss and wasting section of the training manual.

intent-to-treat analysis (ITT) and on-treatment analysis (OT) – two important ways that trial results are analysed. ITT includes all patients who entered the study and is more rigorous. OT only calculates the response rates for people still on the randomised treatment.