HTB | HIV i-Base

HTB

Ending 2020 with positive news on vaccines against COVID-19... plus treatment, research, HIV and more...

Featured HTB: no. 13/14 – HIV and COVID-19: issue 10 (9 December 2020) 9 December 2020. Related: Editorial.
Featured HTB: no. 12 – HIV and COVID-19: issue 9 (11 November 2020) 11 November 2020. Related: Editorial.
Featured In Memory: Timothy Ray Brown, the Berlin patient, the first person to be cured of HIV 14 October 2020. Related: In Memory.
Latest update on HIV and COVID-19 from BHIVA and EACS (January 2021) 15 January 2021. Related: Early access, COVID-19: HIV and COVID-19 coinfection, COVID-19.
Baseline NNRTI resistance linked to poorer response to first-line dolutegravir in the ADVANCE study 14 January 2021. Related: Early access, Treatment strategies, Resistance.
Monoclonal antibody bamlanivimab is not effective in advanced COVID-19: lack of early signal stops study early 10 January 2021. Related: Early access, COVID-19: investigational drugs, COVID-19.
Novavax phase 3 vaccine study launched in the UK, South Africa, US, Mexico and Puerto Rico 10 January 2021. Related: Early access, COVID-19: vaccine, COVID-19.
Pfizer COVID-19 vaccine might still overcome UK and SA variants 10 January 2021. Related: Early access, COVID-19: vaccine, COVID-19.
HIV criminalisation during 2020: cases continue but also legal advances 10 January 2021. Related: Early access, OIs, coinfections and complications, Other news.
Significant increases in LGV in gay men from 2017 to 2019: latest PHE report 10 January 2021. Related: Early access, OIs, coinfections and complications, Other news.
Azithromycin monotherapy shows no benefit for COVID-19: RECOVERY study reports 1493 further deaths 7 January 2021. Related: Early access, COVID-19: investigational drugs, COVID-19: research studies, COVID-19.
WHO strongly recommended against using hydroxychloroquine or lopinavir/r at any stage of COVID-19 7 January 2021. Related: Early access, COVID-19: investigational drugs, COVID-19: guidelines, COVID-19.
US guidelines for using mRNA vaccines against COVID-19 5 January 2021. Related: Early access, COVID-19: vaccine, COVID-19: guidelines, Future meetings.
Very low-level viral load viraemia might continue after COVID-19 5 January 2021. Related: Early access, COVID-19: pathogenesis, COVID-19.
Updated US guidelines for treating COVID-19 (December 2020) 5 January 2021. Related: Early access, COVID-19: guidelines, COVID-19.
Webcasts of two-day US Workshop on long COVID now online 5 January 2021. Related: Early access, COVID-19: pathogenesis, COVID-19.
US update guidelines on access to COVID vaccines 4 January 2021. Related: Early access, COVID-19: vaccine, COVID-19: treatment access, COVID-19: guidelines, COVID-19.
NICE issue UK guidelines on long COVID 2 January 2021. Related: Early access, COVID-19: guidelines, COVID-19: pathogenesis, COVID-19.
Long-acting injectable HIV treatment from ViiV Healthcare approved in the EU 2 January 2021. Related: Early access, Antiretrovirals.
i-Base appeal: please support i-Base with £5 or £10 a month 9 December 2020. Related: Editorial.
BHIVA 2020 virtual conference 9 December 2020. Related: Conference reports, Conference index, BHIVA 2020 virtual.
Worryingly low HIV knowledge among health workers at London hospital: 80% unaware of U=U, 36% worried about their risk from patients 9 December 2020. Related: Conference reports, HIV prevention and transmission, BHIVA 2020 virtual.
12th International Workshop on HIV paediatrics 9 December 2020. Related: Conference reports, Conference index, 12th Paediatric HIV 2020.
Dolutegravir dosing for infants and young children 9 December 2020. Related: Conference reports, Paediatric care, 12th Paediatric HIV 2020.
EU approves dolutegravir 5 mg dispersible for children older than four weeks 9 December 2020. Related: Antiretrovirals, Paediatric care.
New formulation of dolutegravir will make modern ART available for babies and young children at less than $120 a year 9 December 2020. Related: Antiretrovirals, Treatment access, Paediatric care.
Innovation benefits of cabotegravir LA injections for HIV PrEP will enable a closer FDA review 9 December 2020. Related: HIV prevention and transmission.
World AIDS Day 2020: selected events 9 December 2020. Related: Other news.
Once-monthly oral pill as PrEP against HIV: islatravir study to start in 2021 9 December 2020. Related: HIV prevention and transmission.
High rates of drug resistance and virological failure among adults with HIV admitted to hospital in Malawi 9 December 2020. Related: Resistance.
Recent studies on HIV and COVID-19 coinfection 9 December 2020. Related: COVID-19: HIV and COVID-19 coinfection, COVID-19.
Early safety and immune responses in older people using the Oxford vaccine: overall results complicated by dosing error 9 December 2020. Related: COVID-19: vaccine, COVID-19.
BHIVA statement on HIV positive people and access to COVID vaccines 9 December 2020. Related: COVID-19: HIV and COVID-19 coinfection, COVID-19: vaccine.
Interim results report 94% efficacy with Moderna/NIH mRNA vaccine: FDA hearing on 17 December 9 December 2020. Related: COVID-19: vaccine, COVID-19.
HIV risk from some COVID-19 vaccines might be unlikely due to rarity of vector viruses involved 9 December 2020. Related: COVID-19: vaccine, COVID-19.
Hydroxychloroquine fails to prevent COVID-19 or SARS-CoV-2 transmission when used as PEP 9 December 2020. Related: COVID-19: investigational drugs, COVID-19: transmission & prevention, COVID-19.
Hydroxychloroquine has no benefit on symptoms at 14 days 9 December 2020. Related: COVID-19: investigational drugs, COVID-19.
WHO SOLIDARITY study published in NEJM 9 December 2020. Related: COVID-19: investigational drugs, COVID-19.
International COVID-19 study launches in Africa but with drugs that have little chance of working (ANTICOV) 9 December 2020. Related: COVID-19: investigational drugs, COVID-19: research studies, COVID-19.
Serious complications commonly reported three months after recovery from COVID-19 9 December 2020. Related: COVID-19: complications, COVID-19: pathogenesis, COVID-19.
HTB no 13–14 – plus: HIV and COVID-19 bulletin no 10 (9 December 2020) 9 December 2020. Related: PDFs.
HIV in the UK: diagnoses continued to fall during 2019 but 42% are still late 11 November 2020. Related: HIV prevention and transmission.
HIV Therapy Glasgow 2020 11 November 2020. Related: Conference reports, Conference index, Glasgow 2020.
Adverse pregnancy outcomes among Spanish women hospitalised with COVID-19 11 November 2020. Related: Conference reports, Pregnancy, COVID-19: transmission & prevention, COVID-19, Glasgow 2020.
51st World Conference on Lung Health 11 November 2020. Related: Conference reports, Conference index, World Conference on Lung Health 51st 2020.
No increase in adverse birth outcomes with IPT-exposure in pregnancy in two African cohorts 11 November 2020. Related: Conference reports, Pregnancy, TB coinfection, World Conference on Lung Health 51st 2020.
International workshop on clinical pharmacology of HIV, hepatitis, and other antiviral drugs 11 November 2020. Related: Conference reports, Conference index, PK Workshop 2020.
New neonatal liquid formulations of dolutegravir have comparable bioavailability to dispersible paediatric tablet 11 November 2020. Related: Conference reports, Antiretrovirals, Paediatric care, PK and drug interactions, PK Workshop 2020.
EMA issues positive opinion to approve cabotegravir LA/rilpivirine LA injections (Vocabria/Rekambys) as new HIV treatment 11 November 2020. Related: Antiretrovirals.
Two-monthly cabotegravir injections prevent HIV infection in African women: HPTN 084 study recommends early unblinding 11 November 2020. Related: HIV prevention and transmission.
AIDS 2020: Virtual online translated resources 11 November 2020. Related: On the web, IAS COVID-19 virtual 2020.