Guides

Continued use of efavirenz

As mentioned earlier, efavirenz is no longer a preferred drug in the UK treatment guidelines (or in US or European guidelines).

This is because although efavirenz has a long history of being widely used and is now very cheap, many people have difficult side effects.

Some regions in the UK might continue to use this drug for the cost savings. As side effects often become manageable within a few weeks, some people might still be asked to try efavirenz first.

The only way this proposal will work will be for people who have side effects to be able to easily change if they have problems.

No one in the UK should have to put up with side effects from efavirenz.

This means if you find that efavirenz affects your sleep, your moods or your confidence, or if it makes you feel more anxious and nervous, your treatment should be switched to an alternative HIV drug.

Efavirenz should not be prescribed for anyone who is anxious or depressed or who has a history of these symptoms. It should not be precribed for people who work shifts.

Last updated: 1 October 2019.