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The PROUD study: access to PrEP in the UK to prevent HIV

At the end of last week I posted two new articles on the i-Base website. The first was an announcement about changes to the PROUD study. The second was a Q&A page about the change and about PrEP in the …

HIV and young gay people in London: two short online videos

More a plug for two new online videos than a blog, these links relate to a public event held in Soho a couple of weeks ago. The first video is 12 minutes long and edits interviews with five young gay …

UK changes PEP meds: raltegravir replaces PIs

The UK has dropped the use of protease inhibitors (PIs) in combinations for Post Exposure Prophylaxis (PEP). This refers to when an HIV negative person uses HIV drugs for one month immediately after a risk for HIV – usually a …

HIV, gay men and drug use: ASTRA study and comment in The Lancet HIV

A research group I am involved with has just had a paper published in the new online publication The Lancet HIV. This paper is available free in full. [1] This is interesting for compiling results from one of the biggest …

START study open DSMB report (May 2014)

The latest open report from the Data and Safety Monitoring Board (DSMB) for the international randomised START study is now online. START looks at the risks and benefits of immediate treatment (at any CD4 count above 500 cells/mm3) compared to …

Generic ARVs in the UK – background paper for drug commissioning

Leaflet in PDF format (82 Kb) New commissioning guidelines for London – April 2014. Introduction by i-Base This paper was originally drafted in 2012 as a discussion paper for the London HIV Consortium HIV and Drugs sub-committee, which I have been …

The importance of evidence for “When to Start”: a response to Dr Myron Cohen

Simon Collins, HIV i-Base This article is prompted by approaches to the debate about when to start HIV treatment, which avoid both the complexity and lack of evidence to inform this key issue for HIV positive people, doctors and health …

d4T – Time to move on

The first conference of the Southern African Clinician’s Society burst into life with a demonstration by the Treatment Action Campaign (TAC). TAC were unequivocal that repurposing d4T at any dose is not an acceptable way to conquer cost concerns with treatment scale …

Treatment optimisation: technical updates from WHO

Tucked away before the slog of the International AIDS Conference, the elation of the Olympics and the despair at the appointment of our new health minister, was the release of three technical updates by the World Health Organization (WHO). These …

Film review: How to survive a plague – the early years of ACT-UP New York

On Monday evening, a few blocks south of the conference centre, a preview screening took place for a film tracking ACT-UP from the first meetings though to the arrival of the first effective treatments. The film tells the story of …

Pictures from the march in Washington

A few pictures from marches and demonstrations held in Washington yesterday to focus on global health and access to HIV treatment. At the end of the rally, as an extension of the peaceful protest, a smaller group of activists used …

START study: enrolling well, open DSMB report shows no concerns

In Washington, prior to the World AIDS Conference, the INSIGHT research group is holding several meetings relating to the START study. Of these, I  am attending the Community Advisory Board today and the Scientific Steering Committee tomorrow. Also tomorrow, there …

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