26 August 2012. Related: ARVs, PIs.
- Fosamprenavir (tradenames Telzir in Europe and Levixa in the US) is a protease inhibitor. Fosamprenavir needs to be boosted by a separate dose of ritonavir.
- Standard adult dose: 1 x 700 mg table, twice-daily. Each dose taken with a separate dose of ritonavir. Other doses are possible in some patients.
- Fosamprenavir can be taken with or without food.
- Side effects: nausea, rash, changes in lipids (blood fat) which should be routinely monitored, lipodystrophy (fat accumulation) and diarrhoea.
- Other notes: St John’s wort should not be used with fosamprenavir.
Information on lipodystrophy from the i-Base side effects guide.
The European patient information and detailed Product Information for fosamprenavir are available from this link on the European Medicines Agency (EMA) website.
The Patient Information is a simplified summary: what the drug is, why it is used, results from studies and cautions including side effects.
The Product Information is a detailed technical summary that you can access as a PDF file by clicking the ‘Product Information’ tab. It describes more precisely how the drug works and how it is processed by your body. This includes, for example, reported food interaction studies in terms of calories or fat content. It includes more details of the study results and a full list of side effects and drug interactions.