What about side effects?

Modern ART has a very low risk of serious side effects.

Any side effects are usually mild and improve within a few weeks.

But if side effects continue, please talk to your clinic. If they continue it is sometimes easy to try a different ART.

More information on side effects is included later in this guide.

These links also have more information.

• What is the risk of side effects?
• Weight increases on ART
• Metabolic changes and other body changes
• Other side effects and health issues

Over many years I have changed treatment several times.

This has always been because of a side effect or because newer drugs were easier to take or more effective.

Every time, this ended up being better for my health – even though I am always nervous when changing meds.

— Mike, London

Last updated: 1 October 2026.