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1 December 2011. Related: On the web.

PLoS Medicine

Optimal uses of antiretrovirals for prevention in HIV-1 serodiscordant heterosexual couples in South Africa: a modelling study. Hallet TB et al.

PLoS Medicine Volume 8 (11) November 2011.

http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001123

Timothy Hallett and colleagues use a mathematical model to examine the long-term impact and cost-effectiveness of different pre-exposure prophylaxis (PrEP) strategies for HIV prevention in serodiscordant couples.

Cost-effectiveness of early versus standard antiretroviral therapy in HIV-infected adults in Haiti. Koenig SP et al.

PLoS Medicine Volume 8 (9) September 2011.

http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001095

In a cost-effectiveness study, Bruce R Schackman and colleagues compares early versus standard antiretroviral treatment (ART) for HIV, based on randomised clinical trial data from Haiti, revealing that the new WHO guidelines for early ART initiation can be cost-effective in resource-poor settings.