HTB

Conference reports

Glasgow HIV Congress (2018) – second reports

Hepatitis C is an independent risk factor for preterm delivery in HIV positive women: data from a Warsaw cohort

Vertical transmission remains very low in UK and Ireland: update from the National Study of HIV in Pregnancy and Childhood 

3rd HIV Research for Prevention Conference (R4P2018) – second reports

3D printing technology has potential to individualise production of vaginal rings

22nd International AIDS Conference (AIDS 2018) – final report

No significant decrease in raltegravir free fraction during pregnancy

Glasgow HIV Congress (2018)

No additional neural tube defects with preconception dolutegravir: data from three birth outcome cohorts

Insufficient data on risk of neural tube defects with exposure to elvitegravir or bictegravir exposure during preconception or first trimester

Viral dynamics of dolutegravir-based dual versus triple ART

Ibalizumab: 48-week phase 3 results in 27 participants with MDR HIV

Fostemsavir: 48-week phase 3 results from BRIGHTE study

Dolutegravir non-inferior to low dose efavirenz in real-life African study conducted in Cameroon  

3rd HIV Research for Prevention Conference (R4P2018)

How to evaluate PrEP and vaccines: urgency for next generation compounds

Dual bNAb maintains viral suppression for median 21 weeks off-ART

Cabotegravir levels can be detected several years: PK tail to be covered by oral PrEP

3D imaging show HIV infection might establish within hours

bNAbs for HIV prevention: extended-release VRC01, AMP study, 10E8 safety signal and pan-clade challenges

Why U=U does not cover breastfeeding

BHIVA Autumn Conference 2018

Second case of potential HIV eradication

New UK PrEP guidelines 2018

Other selected talks at BHIVA Autumn 2018

9th International Workshop on HIV and Ageing

Detectable viral load quadruples odds of recurrent falls in older men with HIV

More than 40% of HIV group has hepatic steatosis, regardless of age

Associations of loneliness with cognitive function and quality of life (QoL) among older adults living with HIV – 18% lonely quite often

Physical function worse in older women than men with HIV, despite better CD4 recovery

22nd International AIDS Conference (AIDS 2018) – third reports

Dolutegravir twice daily is effective and tolerable with rifampicin: 48 week results from the INSPIRING study

TAF exposures during pregnancy and postpartum appear adequate but more data are needed

High rate of unintended pregnancy among HIV positive African women on ART

22nd International AIDS Conference (AIDS 2018) – second reports

Namibia close to achieving 90-90-90 targets

Dolutegravir monotherapy: still no longer recommended in either research or clinical practice

Changing comorbidities in HIV positive people older than 60 at London clinic

High acceptability of annual digital (finger) exam for early detection of anal cancer in gay men >35 years old

High rates of anal HPV infection in gay men using PrEP in IPERGAY: the role of vaccination

HCV incidence and reinfection in HIV negative gay men using PrEP in the Netherlands

FDA-approved compounds that might selectively reverse HIV latency

Lack of impact on viral reservoir with α4β7 monoclonal antibody vedolizumab: macaque results not matched in humans

Janssen HIV vaccine: update from APPROACH and largescale efficacy study

Viral load testing in Latin America and the Caribbean

Access to viral load testing increased from 14% to 61% over two years in Côte d’Ivoire

Resolving a diagnosis for people with persistently indeterminate HIV test results

10th International Workshop on HIV Paediatrics – second reports

Dolutegravir dispersible tablets for infants and young children: early PK, safety and efficacy

22nd International AIDS Conference (AIDS 2018) – first reports

Caution on press conference news from AIDS 2018

Zero HIV transmissions in PARTNER 2 study after gay couples had sex 77,000 times without condoms – an undetectable viral load stops HIV

DTG/3TC dual therapy is non-inferior to triple-ART in GEMINI study

Once-daily reduced dose darunavir/ritonavir (400 mg/100 mg) is non-inferior to twice-daily lopinavir/ritonavir in South African switch study  

Superior efficacy with dolutegravir-based ART compared with other regimens at 6 months: real-world data from Brazil 

WHO recommends dolutegravir widely but women’s access will depend on contraception provision

No additional neural tube defects among a further 170 preconception dolutegravir exposures in Botswana: Tsepamo study (July 2018)

Swifter viral load suppression with dolutegravir vs efavirenz in late pregnancy: results from DolPHIN 1

First randomised kick-and-kill cure study fails to reduce HIV reservoir: RIVER study reports vorinostat and vaccines show activity, but not enough

Using PrEP with feminising hormone therapy supports daily PrEP dosing for transwomen

Daily and on-demand PrEP both prevent HIV in Prévenir study: high adherence by gay Parisians

AIDS 2018 online: links to selected webcasts

10th International Workshop on HIV Paediatrics – first reports

Preconception safety signal with dolutegravir: data from the Tsepamo study

What to watch: HIV cure-related research at AIDS 2018

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