May 2025

Contents

Journal scan

• Vaccination is effective in limiting mpox progression – but lower efficacy in people living with HIV

• HIV activists in the US call for action in JID and Zachie Achmat brings South African perspective in the Lancet

• Combining injectable lenacapavir and cabotegravir-LA

Special reports

• The Denver Principles – riso print by Jane Shepherd to support i-Base

• Reduced dosing: a possible crisis response to ART stockouts and closed clinics

Treatment access

• Scientific, legal and ethical crisis from halting ongoing NIH studies: TAG statement

• Impact of US funding cuts in Malawi and South Africa: ITPC community report

• Closed clinics and limited ART in Zimbabwe, PEPFAR and UNAIDS news

Guidelines

• IAS-USA update drug resistance mutations (2025)

• US updates guidelines for statin use in people living with HIV

• US CDC updated guidelines on PEP (May 2025)

Side effects

• Yellow card reporting scheme for doctors and patients in the UK