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COVID-19

COVID update: new waves of BA.4 and BA.5 in the UK – all omicron variants linked to reduced antibody responses to vaccines

Importance of booster vaccine to protect against emergent COVID-19 variants

Similar COVID-19 vaccination responses in HIV positive people on ART and with good CD4 counts compared to HIV negative controls

US study reports higher rates of breakthrough COVID in HIV positive vs negative controls

BMJ reports UK government failed to protect doctors during COVID-19

Implications of SARS-CoV-2 in gut tissue for transmission of COVID-19 and long COVID

CROI 2022: Other COVID-19 studies

Asymptomatic COVID-19 is common in people living with HIV

Longest COVID-19 infection lasted 505 days in an immunocompromised person in London

Herd immunity unlikely to control COVID-19: opinion article from US NIAID

The challenges of prioritising access to molnupiravir and nirmatrelvir–ritonavir for COVID-19

Increased risk of blood clots after COVID-19: higher with underlying conditions and more severe symptoms

Two new platform vaccines against COVID-19 report phase 3 results

CROI 2022: Long COVID persists for over a year: evidence for divergent immune responses

Temporary protection against omicron needs mRNA booster: limited data for those at highest risk

Efficacy of mRNA vaccines in people with HIV or solid transplant recipients

Long COVID may be more common in people living with HIV

Major review finds little benefit of remdesivir in people hospitalised with COVID-19

Resources on Long COVID

WHO webinars: COVID-19 Global Research and Innovation Forum

UK RECOVERY study shows no benefit from aspirin in people hospitalised with COVID-19

IDSA update COVID-19 guidelines (January 2022)

Reducing the risk of COVID-19 in research that involves interrupting ART

New BHIVA statements on HIV and COVID-19 (December 2021)

Myocarditis and pericarditis after COVID-19 vaccines

WHO advises against use of convalescent plasma for COVID-19

Colchicine: no clinical benefits against COVID-19 in pooled analysis of RCTs

Eli Lilly withdraw EU application for bNAbs etesevimab and bamlanivimab

Reduced responses to COVID-19 vaccines at low CD4 counts

Continued evidence for poorer COVID-19 outcomes in people with HIV  

Immune responses to natural COVID-19 infection in HIV positive people

Durability of immune responses to COVID-19 vaccines in HIV positive people

Sputnik V vaccine not approved in South Africa due to potential increased risk of HIV

Sanofi reports phase 1/2 mRNA results but withdraws from further COVID19 vaccines

Early efficacy results with oral molnupiravir focuses attention on price and access

BHIVA statements on third vaccine doses for people living with HIV

HIV increases risk of severe COVID-19 in largest US study

SARS-CoV-2 variants and immunosuppression

UK vaccine programme saved 100,000 lives

Large US registry confirms safety of COVID-19 vaccines during pregnancy

US FDA grants full approval to Pfizer vaccine

Immune responses against Delta variant in people vaccinated in the UK

Neutralising antibody levels from COVID vaccines correlate negatively with age

Evolution of neutralising antibody responses to natural infection and after vaccination

Outbreak of 469 symptomatic Delta cases in fully vaccinated adults during Bear Week

IAS 2021: WHO report links HIV to 30% increased mortality from COVID-19: based on South African data

Antibody responses to Pfizer vaccine in HIV positive people with high CD4 counts

Third dose of mRNA vaccine improves antibody responses in kidney transplant recipients

US CDC recommends third vaccine dose in some groups

Pfizer plans for third dose: questions over population need?

Efficacy of Oxford/AZ and Pfizer vaccines against Delta variant in the UK

Results from Novavax phase 3 study in the UK

WHO approves Chinese vaccines for emergency use

Selected other vaccine studies

Efficacy of Chinese CoronaVac vaccine in Chile national programme

NHS supports selected use of inhaled budesonide for COVID-19 in people at risk of severe events

Reviews of ivermectin for COVID-19: evidence from RCTs is still needed

RCT shows no impact of azithromycin in reducing symptoms of mild COVID-19

Variation in ACE2 levels are not related to outcomes from COVID-19

London HIV study of responses to COVID-19 vaccines and natural infection (SCAPE)

mRNA vaccine fails to produce antibody response in late-stage HIV: low CD4 count and high viral load

Special report on background incidence of adverse events in vaccine studies

Third vaccine dose increases immune response to 68% in French transplant recipients

Third COVID-19 vaccine dose in US cohort of people on immune-suppressing treatment: safety and ethical issues

Plans for universal third vaccine dose for UK adults from September

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