Resources on Long COVID

Simon Collins, HIV i-Base

Many of the following links were included in previous issues of HTB. Other related resources are added below.

Symptoms and risk factors for long COVID in non-hospitalized adults. Subramanian A et al. Nat Med (2022). doi: 10.1038/s41591-022-01909-w.
https://www.nature.com/articles/s41591-022-01909-w
Large retrospective matched cohort study using a UK-based primary care database with roughly 500,000 cases and 2 million controls.

Health outcomes in people 2 years after surviving hospitalisation with COVID-19: a longitudinal cohort study, Huang L et al. Lancet Respiratory Medicine. DOI:10.1016/S2213-2600(22)00126-6. (11 May 2022).
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(22)00126-6/fulltext
This paper reports that 55% of people still have one related symptom more than two years after COVID-19.

UK Independent SAGE webinar on Long COVID (17 June 2022).
https://www.youtube.com/watch?v=g60waH14oZg

MMWR review estimates 1 in 5 people have at least one symptoms that qualifies as long COVID.
Bull-Otterson L et al. Post–COVID Conditions Among Adult COVID-19 Survivors Aged 18–64 and ≥65 Years — United States, March 2020–November 2021. MMWR Morb Mortal Wkly Rep 2022;71:713–717.
http://dx.doi.org/10.15585/mmwr.mm7121e1.

Upcoming virtual workshop:
Long-Term Health Effects from COVID-19 and Implications

Monday, March 21, 2022 – 10:30am – 4:00pm US Eastern time
Tuesday, March 22, 2022 – 10:30am – 3:30pm US Eastern time

The National Academies will hold a public workshop to explore the long-term and potentially disabling health effects stemming from COVID-19 infection and how they might impact survivors’ ability to work.
Free registration.

Long COVID may be more common in people living with HIV
HTB review of small US study (Peluso et al, see below).
https://i-base.info/htb/42389

Post-acute sequelae and adaptive immune responses in people living with HIV recovering from SARS-COV-2 infection. Peluso MJ et al. Preprint. medRxIV. (14 February 2022).
https://www.medrxiv.org/content/10.1101/2022.02.10.22270471v1.full

Post-acute effects of SARS-CoV-2 infection in individuals not requiring hospital admission: a Danish population-based cohort study. Lund LC et al. Lancet Infect Dis.2021. (Oct 2021).
https://doi.org/10.1016/S1473-3099(21)00211-5

Outcomes at 6- and 12-months in >1200 adults with COVID-19 in Wuhan, China. Approximately 50% reported at least one complication sustained to 12 months.
Ref: Huang L et al. 1-year outcomes in hospital survivors with COVID-19: a longitudinal cohort study. Lancet. DOI: 10.1016/S0140-6736(21)01755-4 (28 August 2021).

Lancet editorial. DOI: DOI: 10.1016/S0140-6736(21)01900-0. (28 August 2021).
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01900-0/fulltext

The HIV Movement Must Come Through
JD Davids in POZ magazine. (June 2021)
https://www.poz.com/article/hiv-movement-must-come-through

Long-time HIV activist JD Davids, writes about approaches to managing Long COVID through their experience of living with myalgic encephalomyelitis (ME) and lessons from HIV activism. Also includes a resources section.

Long COVID website
https://www.longcovid.org

One of the early and leading community websites

Body Politic website
https://www.wearebodypolitic.com/covid19

Another early peer-led community website.

HTB report on meeting and webcasts from an important 2-day NIH workshop on Long COVID with online links.

NIHR. Living with COVID-19.
https://evidence.nihr.ac.uk/themedreview/living-with-covid19

NICE issue UK guidelines on long COVID
HTB (22 January 2021).
https://i-base.info/htb/39597

Summary of UK guidelines for health workers managing Long COVID.

Pathogenesis and treatment of COVID-19 including Long COVID
HTB (14 October 2020).
https://i-base.info/htb/39054

HTB report of an excellent talk by Professor Karine Lacombe from the Glasgow HIV Congress.