tenofovir alafenamide (TAF)

21 June 2026. Related: ARVs and PrEP, Nukes, PrEP.

No picture: TAF is only available in coformulations with other HIV drugs.

ten-OFF-o-vir  AL-af-en-uh-myde (TAF)

Tenofovir alafenamide (TAF) is a more recent version of tenofovir DF (TDF).

• TAF uses a low milligram dose (25 mg).
• TAF has similar efficacy against HIV as TDF.
• TAF has lower risk of kidney and bone side effects compared to TDF.
• It is also used in combination with emtricitabine (FTC) by HIV negative people as PrEP.

TAF is only available in formulations with other HIV meds in the same pill.

• Descovy (TAF plus emtricitabine).
• Odesfey (TAF plus rilpivirine plus emtricitabine).
• Genvoya (TAF plus elvitegravir plus cobicistat plus emtricitabine).
• Biktarvy (TAF plus emtircitabine plus bictegravir).