Updates in this edition, disclaimer and credits
This is the 10th edition of this guide. It has been updated throughout and includes important (and exciting) new information.
- Everyone who can benefit from PrEP should now be able to get it. You no longer have to be at high risk.
- Everyone can also quick-start PrEP with a double dose, getting protection within two hours.
- Event-based dosing can also now be used by everyone, whatever your exposure risk. This uses either 2:1:1 or 2:7 dosing.
- New info covers starting and stopping PrEP and new versions of PrEP (TAF/FTC and injectables).
- UK PrEP guidelines are also being updated for 2024.
The first edition of this guide was first produced in June 2016.
It has been updated at least every year since to includes information about access to PrEP in the UK and how it can be used by different groups of people.
This guide is dedicated to our inspirational co-author Dr Mags Portman who was a leading advocate for PrEP in the UK. Mags died from mesothelioma in February 2019 aged 44. We miss her deeply.
Disclaimer
Information about PrEP can change based on new research.
Information in this booklet is meant to be used in discussion with your doctor.
Further information
This leaflet was produced by doctors and community advocates from the following organisations.
- BASHH special interest group MSM
www.bashh.org - HIV i-Base
www.i-base.info - iwantprepnow.co.uk
www.iwantprepnow.co.uk - PrEPster.info
www.PrEPster.info - 56 Dean Street
www.dean.st - Mortimer Market Centre
www.sexualhealth.cnwl.nhs.uk/clinic/mortimer-market-centre-including-margaret-pyke-centre - CiniQ: sexual health and well-being for trans people
www.cliniq.org.uk - Sophia Forum
sophiaforum.net - PrEP in Scotland
prep.scot - PrEP in Wales
www.shwales.online/wales-prep-project.html - PrEP in N. Ireland.
rainbow-project.org/prep - IMPACT trial
prepimpacttrial.org.uk - Drug interactions
hiv-druginteractions.org - PrEP guidelines
bashh.org and bhiva.org - HPV vaccine for gay men
i-base.info/htb/31151
Credits
Written by Dan Clutterbuck, Simon Collins, Sheena McCormack, Achyuta Nori, Will Nutland, Greg Owen, Mags Portman, Michelle Ross, Sophie Strachan, Martina Toby, Laura Waters, Ashwin Caffery and Aedan Wolton.
Thanks to the Chelsea and Westminster NHS Trust for help with printing.
Cover graphic: iwantPrEPnow.co.uk
ISSN 2398-6409 (i-Base, London, 10th edition, February 2024).
Last updated: 1 February 2024.