Is PEP recommended if I am on PrEP?

PEP stands for post-exposure prophylaxis and involves taking a combination of three HIV meds for one month.

PEP stands for post-exposure prophylaxis and involves taking a combination of three HIV meds for one month.

PEP is now used less often. But if you need PEP, the earlier you start, the more likely it is to work. 

Ideally, PEP should be started within 24 hours.

In the UK PEP can be started up to 72 hours after sex.

There is no benefit from starting PEP after more than 72 hours.

• If you have a risk when you haven’t been taking PrEP, or enough PrEP, contact a doctor to discuss whether you might need PEP. 
• Take a double dose of PrEP asap (if you still have some). This will cover you while you are trying to access PEP. 
• You can get PEP from your clinic or from A&E when your clinic is closed. A&E departments are open 24 hours a day, 7 days a week. 

Last updated: 1 February 2024.