Updates in this edition, disclaimer and credits

Updates in this edition

This is the fifth edition of a booklet that was first produced in June 2016 and reprinted in November 2016, March 2018 and March 2019. This edition has been updated throughout. It includes new information about access to PrEP in the UK and also on PrEP and sex work

This guide is dedicated to our inspirational co-author Dr Mags Portman who was a leading advocate for PrEP in the UK. Mags died from mesothelioma in February 2019 aged 44. We miss her deeply.


As information about PrEP is likely to change based on new research please the online version on the i-Base website for any updates.

Information in this booklet is meant to be used in discussion with your doctor.

Further information

This leaflet was produced as a collaboration with doctors and community advocates from the following organisations.

Additional links


Written by Dan Clutterbuck, Simon Collins, Sheena McCormack, Achyuta Nori, Will Nutland, Greg Owen, Mags Portman*, Killian Quinn, Michelle Ross, Sophie Strachen, Martina Toby, Laura Waters and Aedan Wolton.

Thanks to MAC AIDS Fund for supporting for this edition.

Cover logo thanks to:

Guide to PrEP (Print) ISSN 2398-6409  (i-Base, London, 3rd edition, September 2017)
Guide to PrEP (Online) ISSN 2398-6417  (i-Base, London, 3rd edition, September 2017)

Last updated: 1 November 2019.