Updates in this edition, disclaimer and credits

This is the 11th edition of this guide.

It is very similar to the 10th edition last year that was updated throughout and included important (and exciting) new information.

  • Everyone who can benefit from PrEP should now be able to get it. You no longer have to be at high risk.
  • Everyone can also quick-start PrEP with a double dose, getting protection within two hours.
  • Event-based dosing can also now be used by everyone, whatever your exposure risk. This uses either 2:1:1 or 2:7 dosing.
  • New info covers starting and stopping PrEP and new versions of PrEP (TAF/FTC and injectables).
  • UK PrEP guidelines are also being updated for 2024.

The first edition of this guide was first produced in June 2016.

It has been updated at least every year since to includes information about access to PrEP in the UK and how it can be used by different groups of people.

This guide is dedicated to our inspirational co-author Dr Mags Portman who was a leading advocate for PrEP in the UK. Mags died from mesothelioma in February 2019 aged 44. We miss her deeply.

Disclaimer

Information about PrEP can change based on new research.

Information in this booklet is meant to be used in discussion with your doctor.

Further information

This leaflet was produced by doctors and community advocates from the following organisations.

Credits

Written by Dan Clutterbuck, Simon Collins, Sheena McCormack, Achyuta Nori, Will Nutland, Greg Owen, Mags Portman, Michelle Ross, Sophie Strachan, Martina Toby, Laura Waters, Ashwin Caffery and Aedan Wolton.

Thanks to the Chelsea and Westminster NHS Trust for help with printing.

Cover graphic: iwantPrEPnow.co.uk

ISSN 2398-6409 (i-Base, London, 10th edition, February 2024).

Last updated: 1 July 2025.