2015 Conference on Retroviruses and Opportunistic Infections (CROI), 23-26 February 2015, Seattle
24 March 2015. Related: Conference reports, Conference index, CROI 22 (Retrovirus) 2015.
The 2015 Conference on Retroviruses and Opportunistic Infections (CROI) was held from 23-26 February in Seattle, Washington.
CROI is the most important annual scientific and medical HIV conference. This year the conference opened with important news on oral pre-exposure prophylaxis (PrEP), including the PROUD and IPERGAY studies, topical PrEP and other HIV prevention options – including research to reduce mother to child transmission. Other key sessions included HIV-related complications, antiretrovirals in the pipeline and HIV pathogenesis – especially in the context of cure research.
Abstracts for each study are available in a searchable online database and some posters are available to download as PDF files.
http://www.croiconference.org/abstracts/search-abstracts
All plenary lectures and oral presentations are online as webcasts.
Articles included in this issue of HTB are:
- Pipeline ART: tenofovir alafenamide (TAF)
- Pipeline ART: maturation inhibitors and an attachment inhibitor
- No HIV transmissions between gay couples when viral load is undetectable: preliminary results from “Opposites Attract” study in Australia, Thailand and Brazil
- PrEP reduced HIV risk by at least 86% in PROUD: no transmissions likely from people taking meds
- “On demand” PrEP dosing in IPERGAY: 86% reduced risk of HIV, no transmissions with active drug use
- Other HIV PrEP studies at CROI 2015: implementation of oral PrEP and problems with tenofovir gel
- Early HIV treatment and isoniazid prophylaxis: why TEMPRANO results do not yet support universal ART at CD4 >500 cells/mm3
- Unintended pregnancies with levonorgestrel implant due to drug interactions with efavirenz-based ART
- Three drug ART best for preventing vertical transmission to infants: results from the PROMISE study
- 3 in 5 breastfeeding women with viral load >1,000 copies/mL are undiagnosed in Kenya, Malawi and South Africa
- Point of care HIV PCR test for infant diagnosis: good performance but poorer results in youngest age group
- Weekend off ART is non-inferior to continuous ART in young people taking efavirenz-based regimens: results from BREATHER study
- Increased cardiovascular risks in HIV positive children in Uganda and Zambia partially reversed by ART
- Lopinavir/ritonavir in young children is superior to nevirapine after five years: results from long term follow up of IMPAACT P1060
- Long-term safety and efficacy of tenofovir in children
- UK case of HIV remission: ten years off-ART in patient with prior progression and treated during seroconversion