14th Conference on Retroviruses and Opportunistic Infections, 25-28 February 2007, Los Angeles

5 May 2007. Related: Conference reports, Conference index, CROI 14 (Retrovirus) 2007.

Reports from the conference

As usual with CROI, we include reports from this conference over several issues of HTB. The last issue of HTB included reports on new drugs, pregnancy, side effects, resistance, hepatitis, oncology, pharmacokinetics and drug interactions.

Reports in the issue cover pregnancy, MTCT, paediatrics, neurology and genomics studies:

• No benefit of early cessation of breastfeeding in the Zambia Exclusive Breastfeeding Study (ZEBS)

• Role of infant feeding and HIV in a severe diarrhoea outbreak in Botswana

• Diarrhoea in uninfected infants of HIV-positive mothers who stop breastfeeding at 6 Months

• Post-weaning gastroenteritis and mortality in HIV-uninfected infants receiving antiretroviral prophylaxis

• Rates of diarrhoea associated with early weaning among infants in the Kisumu breastfeeding study

• Early breastfeeding cessation among infants and risk of serious gastroenteritis: findings from a perinatal prevention trial in Kampala, Uganda

• Treating children in resource-limited settings

• Pharmacokinetics of nevirapine, d4T, and 3TC in Zambian children treated with Pedimune (Triomune)

• New PK data for protease inhibitors

• Plasma concentrations of efavirenz and lopinavir in children with and without rifampicin-based TB treatment

• NNRTI vs PI HAART regimens for children in resource-limited settings

• Predictors of infant mortality

• HIV-infection in the brain, neurocognitive dysfunction and CNS drug penetration

• Selected genetics studies from CROI

• Report from genomics workshop at CROI

Unless stated otherwise, references are to the Programme and Abstracts for the 14th Conference on Retrovirus and Opportunistic Infections, available online. Webcasts (including slides) and podcasts are also available on the site.

Programme and abstracts

http://www.retroconference.org

The CROI website makes all key lectures and oral presentations available online, and includes online searchable free access to the abstracts from the meeting. An increasing proportion of poster abstracts are also posted online in PDF format (though this is still only for a minority of the posters).

This broad access means that it is easy to see important trial results and overview lectures directly – this is better that through a community or medical journalist – and the questions and discussion at the end of each session are also included in these web presentations.

We encourage readers to find a few hours to follow some of this important material first hand.