September 2025

Contents

Conference reports

• IAS 2025 conference now open access

Antiretrovirals

• Lenacapavir injectable PrEP approved in Europe – UK application later in 2025

Guidelines

• US guidelines updated: new section on metabolic complications (2025)

HIV prevention and transmission

• UK PrEP booklets now available

• New BASHH report on PrEP access and uptake in the UK

Activism & advocacy

• UN80 plans to dismantle UNAIDS by 2026: sign-on against this now