April 2026

Contents

Journal scan

• Psilocybin is 6-fold more effective than nicotine patches to stop smoking in pilot US study with CBT

Early access

• US FDA approves new once-daily oral HIV combination of doravirine/islatravir

• US CDC stops testing services for key infectious diseases: rabies, mpox, measles, EBV, SARS and others

• Update on Gilead’s once-weekly oral HIV GS-1720 and GS-4182 studies

Conference reports

• CROI 2026: 15 i-Base reports from this essential conference

• CROI 2026: Only three new HIV cases on lenacapavir PrEP: updates from PURPOSE-1 and -2

• CROI 2026: investigational HIV combinations – daily, weekly, 4- and 6-monthly…

• CROI 2026: Persistence and expansion of the HIV reservoir on long-term ART

• CROI 2026: Second course of bNAbs slows viral rebound in RIO study and to lower peak levels

Future meetings

• Future meetings and webinars 2026