Q and A


Could HIV drugs be an annual implant?


Is there any research on a long term medical implant going on ?

I read somewhere a bio degradable implant is being worked on which will last one year. This would effectively be a cure I would think as It would only require yearly or six monthly doctor visits. Surely this would be more cost effective than daily pills ?



You are right that one compound in development might be available as a slow release implant.

The compound is called EFdA and we reported early studies presented at a conference last year. It is also now called MK-8591.

Although an annual implant might be available for this drug, HIV treatment usually needs three drugs in a combination, or sometimes only two. Either way, EFdA will need to be used in combination with other long-activing molecules and currently there are no-other long acting drugs to use with it.

The research into the annual implant therefore is for use by HIV negative people as PrEP – i.e. to prevent infection.

If one drug can be produced with this profile, there is hope that another might be discovered, just that none are available yet.


Your email address will not be published. Required fields are marked *