Q and A


Can I mix doses with different COVID-19 vaccines?


This is a good question that might change in the future, based on new data.

Currently, UK recommendations are to use both the same vaccine for both doses.

However, there are rare times when different vaccines can be used. These include:

  • When protection from the second vaccine is urgent if same vaccine is not available.
  • If there is no record of the make of the first vaccine.
  • In these cases, any second vaccine would be better than missing the second dose.
  • This is NOT a recommendation to routinely mix vaccines.

This is based on guidance in the UK Green Book, chapter 14a.
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/948757/Greenbook_chapter_14a_v4.pdf (PDF)

This is one of more than 45 questions about COVID vaccines. It was produced by and for people living with HIV.
Q&A on COVID vaccines: are they safe and effective?


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