Q and A

Question

How do I change the time I take efavirenz-based ART?

My work schedule changes every 2 months. I take efavirenz, lamivudine, tenofovir. Been UD for 2 years. I take my pill usually at 10:30pm.

But next month my work schedule will be moved till 1 am. I am thinking of moving the time i take my pill at 1 am but I am scared of getting drug resistance. Would it be possible to slowly adjust it per day? Like for example
Monday 10:30pm
Tuesday 11:00pm
Wed 11:30pm
Thursday 12midnight
Friday 12:30am
Saturday 1am.

Or will this risk drug resistance?

Answer

Hi there

Thanks for your email – it is always good to check if you are worried.

The meds in your combination all give your good drug levels that make changing the time very easy.

It is okay to change from 10.30 on one day to 1 am on the next day.

There is no risk of drug resistance from doing this.

best wishes

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