Glossary

Cmin or Ctrough – lowest concentration of a drug just before the next dose.

What happens when you take a drug?

major mutation – a drug resistance mutation that have a big impact on whether a drug continues to work. This used to be called a primary mutation.

jaundice – a common symptom of hepatitis where increased levels of bilirubin lead to a yellowing of the skin or eyes.

substitution therapy – using a prescription drug, eg methadone or buprenorphine, to stop using heroin.

NHL (Non-Hodgkins lymphoma) – a type of lymph cancer.

Cancer: lymphoma and sarcoma