Glossary

codon – the word for the junction on genetic material (DNA or RNA) occupied by three nucleotides (or bases) to form an amino acid. In HIV it is most used when refering to drug resistance. There is an amino acid at each codon and the codons are numbered (starting from 1) for each section of the HIV gene. For example the mutation M184V in RT refers to a mutation change at codon 184 in the reverse transcriptase gene.

seroconversion – the immune reaction when you develop antibodies to a new infection. HIV seroconversion usually starts a couple of week after infection. Because this is when viral load is very high (often millions of copies/mL), this is when symptoms occur.

About 70% people have HIV seroconversion symptoms. Some people become very ill and need immediate ART, and other have no symptoms.

lymph (or lymphatic) system – vessels, nodes, organs and clear fluid, that are part of the immune system.

neutropenia – very low amount of neutrophils (neutrophils are white blood cells that fight bacterial infections).

CD4% – percentage of total lymphocytes (white blood cells) that are CD4 cells.

The CD4% is generally more stable than the CD4 count. For example, if you ever get a CD4 count that is much lower than you expect, first see whether the CD4% has changed too,

If the CD4% is still roughly the same then the low CD4 count is unlikely to show a real change.