Glossary

matched – in clinical trials matched refers to each group having similar age, gender, ethnicity, HIV duration, health etc in a study.

coronary heart disease (CHD) refers to the three main arteries that supply blood from the heart.

A coronary by-pass is a surgical operation to provide a new route for blood to reach the heart when coronary arteries become blocked.

salvage therapy – a term for the combination therapy used after someone has developed resistance to three or more classes of HIV drugs. Also called ‘third-line’ or ‘rescue therapy’ or ‘treatment of patients with multidrug resistance’.

microbicide – a gel that may protect against infection.In reference to HIV, this is usually referring to a gel that could be applied before sex. In 2010 a study called Caprisa 004 provided the first evidence that a microbicide (in this case a gel containing the HIV drug tenofovir) might protect against HIV infection.

adverse event – an unexpected or unwanted effect during a research study. Sometimes this used to describe a side effect from a drug.

Although all side effects are adverse events, not all adverse events are side effects.