Glossary

prophylaxis – a treatment taken before an illness in order to prevent it occuring. Primary prophylaxis is the terming for taking a preventative treatment before ever having had the illness. Secondary prophylaxis is the term for continuing to take a treatment to prevent the illness coming back.

compensatory mutation – this refer to an additional mutation, usually in the context of the fitness of a virus. For example, the mutations that stop a drug form working often stop the virus from reproducing as well. Additional mutations that return the virus to it’s former fitness are called compensatory mutations. They compensate for the reduced viral fitness. See revertant mutation.

randomise – in research, this is a way of decide at random which participants join each group. So neither you or your doctor chose which group you join in a research study. A common example is that the decision would be made similar to tossing a coin.

More information from the i-Base guide to HIV research.

virus – an infectious organism that can only reproduce inside the cell of another plant or animal.

primary mutation – see major mutation.