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Glossary

Selected words and phrases

fixed dose combination (FDC) – several drugs combined in one tablet at a standard dose.

ritonavir – a protease inhibitor (PI) that is now used boost levels of some other  HIV drugs, especially other PIs.

Direct acting antiviral – See DAA.

phenotype — relating to how an organism behaves, based on how its genotype relates to the environment. Phenotypic resistance tests look at whether HIV continues to grow in a test tube after increasing concentrations of a drug are added. See genotype.

sensitivity – when referring to the accuracy of a test result, sensitivity refers to the proportion of people with an illness or disease who have a positive test result.

If a test has low sensitivity, then false-negative results are the concern – where people have a condition but it is missed.

If a test has high sensitivity, then people are accurately diagnosed – and only a few people are missed.

For a serious condition, high sensitivity is essential to be able to identify people early.

Online calculator.

See specificity.

sensitivity – when referring to the activity of a drug, sensitive means that a drug still works. As resistance develops a drug becomes less sensitive.

A complete loss of sensitivity implies that a drug is no longer working.

It also means that your partner may benefit from counselling.