Glossary

CCR5 inhibitor – type of HIV drug (an entry inhibitor) that blocks HIV from getting into a CD4 cell. CCR5 is a co-receptor on the surface of a CD4 cell that HIV uses to attach itself to the cell. CCR5 inhibitors block that process. Maraviroc is currently the only approved CCR5 inhibitor.

Drug targets in the virus life cycle.

C-section – Caesarean section, procedure to deliver a baby that involves making a cut through the abdominal wall to surgically remove the infant from the uterus.

AIDS – acquired immune deficiency syndrome.

antigen – a protein found on the surface of a virus or bacteria. It is recognised by the immune system which then generates antibodies.

epoetin-alpha (EPO) – a treatment for anaemia, given by injection. Used to reduce side effect of hepatitis C treatment.