Immune reconstitution inflammatory syndrome – see: IRIS
Glossary
Selected words and phrases
clinical cut-off (CCO) – a test result that is associated with an impact on clinical care. With resistance tests a lower CCO is the level below which a drug is still sensitive or active. This is often set at a 20% loss of activity (compared to wild-type HIV). An upper CCO is the level above which the drug is not considered active (ie resistant). This is often set at an 80% loss of activity (compared to wild-type HIV).
duration of ruptured membranes – time between when the mother’s waters break and the actual delivery.
sarcoma – medical term for cancer that affects bone, cartilage, fat, muscle, blood vessels, skin or other connective tissue.
Area Under the Curve (AUC) – total exposure to drug over the dosing period.