Glossary

intent-to-treat analysis (ITT) and on-treatment analysis (OT) – two important ways that trial results are analysed. ITT includes all patients who entered the study and is more rigorous. OT only calculates the response rates for people still on the randomised treatment.

baseline – baseline refers to the start of any period being studied. For someone who is HIV positive, their baseline CD4 and viral load counts are the first tests they ever had taken. For someone entering a study, the baseline results refer to their test results at the start of the study. Baseline results for following resistance refers to the results of the first resistance test.

chronic infection – established infection (everything after the first 6 months)

pharmacokinetics – the study of how drugs are absorbed, metabolised and cleared from the body.

antepartum refers to the time during pregnancy before a baby is born. Antepartum refers to the mother.

See: intrapartum and postpartum.