Glossary

steatosis – fatty liver. Build up of fat in the liver. Steatosis worsens liver damage and makes hepatitis C harder to treat.

SIDA – the abbreviation for AIDS in French, Spanish, Italian and Portuguese.

latent – not active at present, resting. Latently infected CD4 cells are CD4 cells that are infected with HIV but which are resting. HIV drugs do not work on resting cells.

clinical cut-off (CCO) – a test result that is associated with an impact on clinical care. With resistance tests a lower CCO is the level below which a drug is still sensitive or active. This is often set at a 20% loss of activity (compared to wild-type HIV). An upper CCO is the level above which the drug is not considered active (ie resistant). This is often set at an 80% loss of activity (compared to wild-type HIV).

secondary mutation – see minor mutation.