clinical cut-off (CCO) – a test result that is associated with an impact on clinical care. With resistance tests a lower CCO is the level below which a drug is still sensitive or active. This is often set at a 20% loss of activity (compared to wild-type HIV). An upper CCO is the level above which the drug is not considered active (ie resistant). This is often set at an 80% loss of activity (compared to wild-type HIV).
Glossary
Selected words and phrases
Hodgkins disease (HD) – a type of lymphoma (lymph cancer).
ritonavir – a protease inhibitor (PI) that is now used boost levels of some other HIV drugs, especially other PIs.
iPrEP (intermittent Pre-Exposure Prophylaxis) – using HIV drugs to before a possible exposure to HIV, to reduce the chance of infection. iPrEP refers to taking a reducing dosing shecdule based on when you are likely to be exposed. PrEP usually refers to a daily treatment.
chorioamnionitis is an inflammation of the membranes that surround the foetus (called the chorion and the amnion). Chorioamnionitis is usually caused by a bacterial infection.