Glossary

HIV – Human Immunodeficiency Virus

confirmatory test – a second test to double-check the results of a previous one. For example, if your viral load is usually undetectable and then becomes detectable, you need a second confirmatory test. This is to check that the detectable result was not a laboratory error on just a temporary blip.

wasting – loss of lean body mass (muscle loss). A unplanned or unexplained wight loss of more than 5% body weight over six months can be an AIDS-defining illness.

Weight loss and wasting section of the training manual.

preclinical refers to the early development stage for a new drug, before any testing on humans. This includes they laboratory and animal tests. Preclinical studies will not always show what will happen when people use the drugs, but can provide a guide to serious problems that could occur.

integrase inhibitor – a type of HIV drug that stops HIV genetic material from ‘integrating’ into the DNA in a cell.

This is a relatively new family of HIV drugs.

Raltegravir, elvitegravir and dolutegravir are all integrase inhibitors.