Glossary

Area Under the Curve (AUC) – total exposure to drug over the dosing period.

weight loss – a general reduction in weight. Weight loss can often be a symptom of other opportunistic infections.

Weight loss and wasting section of the training manual.

CCR5 inhibitor – type of HIV drug (an entry inhibitor) that blocks HIV from getting into a CD4 cell. CCR5 is a co-receptor on the surface of a CD4 cell that HIV uses to attach itself to the cell. CCR5 inhibitors block that process. Maraviroc is currently the only approved CCR5 inhibitor.

Drug targets in the virus life cycle.

fungus (fungi) – parasitic organisms that include moulds, mildews, mushrooms and yeast.

superinfection – another term for reinfection.