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Glossary

Selected words and phrases

entry inhibitor (EI) – class of anti-HIV drug.

Drug targets in the virus life cycle.

ribavirin – drug used to boost the efficacy of pegylated interferon to treat hepatitis C. Given as twice-daily capsules.

informed consent – a document that every person who participates in research is required to sign before entering the study. It outlines the details of a the study, including the known risks and benefits or any intervention. It also explains what is required during the study in terms of additional tests and clinic visits.

surrogate marker – A surrogate marker is when something that is easy to measure is used as a marker for something that is difficult to measure directly.

The CD4 count doesn’t directly measure HIV. But it is a good surrogate (or indirect) marker for how HIV has damaged your immune system. It is closely linked to the risk of HIV-related complications.

Viral load in blood is a good surrogate marker for levels of HIV in your body overall including in other body sites.

MSM – men who have sex with men.