Glossary

in vitro – a study in a test tube. Literally, ‘in glass’.

fold-change – a term relating to drug resistance after a phenotype resistance test.

4-fold resistance (also called a 4-fold loss in sensitivity) means you need to use four times the dose to get the same reduction in viral load.

antiretrovirals – the common name for any HIV drugs. HIV is a retrovirus, so drugs to fight HIV are called antiretrovirals. Also abbreviated to ARVs.

ETR (end of treatment response) – having an undetectable HCV viral load at the end of HCV treatment. See SVR.

Hypotension is the medical name for low blood pressure.

Blood pressure is measured as two numbers ie 120/80. The first number is systolic BP – the pressure when your heart beats. The second number is diastolic BP, which is the pressure when you heart rests between beats.

Target range for BP is usually 120/80.

See: hypertension (high blood pressure).