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Glossary

Selected words and phrases

open label – this means that a patient in a trial knows which treatment they are taking.

coinfection – having more than one infection, eg HIV and TB, or HIV and hepatitis C.

lymph node – small bodies in the lymphatic system, particularly at the neck, armpit, and groin, that filter bacteria and foreign particles. During infection, lymph nodes may become swollen with white blood cells (lymphocytes) fighting the infection.

clinical failure – when you develop new symptoms and illnesses even though you are on treatment. See virological failure.

NNRTI – Non-Nucleoside Reverse Transcriptase Inhibitor, a type of HIV drug – also called ‘non-nuke’.

Efavirenz, nevirapine, rilpivirine, etravirine and doravirine are all NNRTIs.

Drug targets in the virus life cycle.

Listing of NNRTIs.