DEXA – a non-invasive scan that can measure the percentage of different body areas (whole body, trunk, right leg etc) that are muscle or fat. DEXA scans cannot determine if this is central fat (visceral adipose tissue, VAT) or sub-cutaneous fat (under the skin).
DEXA scan also can measure bone density and is used to monitor risk of osteopenia and osteoporosis.
major mutation – a drug resistance mutation that have a big impact on whether a drug continues to work. This used to be called a primary mutation.
bacteria – single-cell micro-organisms without a nucleus.
Cmax – highest concentration of a drug after a dose.
candida – fungus (yeast) infection that affects the mouth and throat, gullet, sinuses, genital organs and – rarely – the brain. Also called ‘thrush’.