Glossary

NNRTI – Non-Nucleoside Reverse Transcriptase Inhibitor, a type of HIV drug – also called ‘non-nuke’.

Efavirenz, nevirapine, rilpivirine, etravirine and doravirine are all NNRTIs.

Drug targets in the virus life cycle.

Listing of NNRTIs.

interaction – when two drugs react to increase or decrease one or both drugs, often in ways that are unexpected or potentially harmful.

clinical failure – when you develop new symptoms and illnesses even though you are on treatment. See virological failure.

minor mutation – a drug resistance mutation that have a big impact on whether a drug continues to work. This used to be called a secondary mutation.

fibrotest – a test which uses results from blood tests to predict liver damage and which may become an alternative option to liver biopsy in some patients.