NRTI – Nucleoside Reverse Transcriptase Inhibitor, a type of HIV drug – also called ‘nuke’ or ‘nucleoside analogue’.
3TC (lamivudine). abacavir, AZT, FTC (emtricitabine), d4T (stavudine), ddI (didanosine) all belong to this class.
Tenofovir DF and tenofovir alafenamide (TAF) are a nucleotide analogues which is similar enough to be counted as part of this class.
Drug targets in the virus life cycle.
nucleus – the central part of some cells that contains DNA.
stage (staging) – the stage of hepatitis infection refers to the amount of scaring (fibrosis), from results from a biposy. It is usually measured on the Metavir scale of 0 to 4, where 0 represents no scarring and 4 cirrhosis, or on the Knodell scale of 0 to 6, where 0 is no scarring and 6 cirrhosis. See grading.
Fibroscan – a non-invasive ultrasound scan that measures the ‘elasticity’ or stiffness of the liver.
i-Base video of a FibroScan on YouTube.
escape mutation – a mutation or change in the genetic structure of HIV that makes it easier to evade the persons immune system (rather than a mutation that stops an HIV drug from working).