Glossary

pegylated interferon (PEG interferon) – treatment for hepatitis C, given in combination with ribavirin. Given as a onceweekly injection.

dyspnoea – medical term for symptoms related to difficulty breathing, shortness or breath.

IRIS (immune reconstitution inflammatory syndrome) – illnesses that occur when HIV treatment is started when the CD4 count is very low.

IRIS occurs because the immune system quickly becomes stronger and identifies infections that it was previously too weak to fight.

IRIS can occur in 1 in 4 (25%) people who start with a CD4 count under 50 cells/mm³.

Although the symtoms are serious, IRIS can usually be easily managed.

Common infections related to IRIS include TB and CMV.

fulminant liver disease – sudden, rapid disease progression related to liver failure.

microbicide – a gel that may protect against infection.In reference to HIV, this is usually referring to a gel that could be applied before sex. In 2010 a study called Caprisa 004 provided the first evidence that a microbicide (in this case a gel containing the HIV drug tenofovir) might protect against HIV infection.