XVI International HIV Drug Resistance Workshop, 12-16 June 2007, Barbados
Although this workshop has a wealth of studies focussing on basic science and more obscure aspects of resitance, research with the most important impact on clinical management is always presented to this meeting first.
Studies reported include:
- Treatment failure and tropism changes in maraviroc trial related to previously undetected CXCR4, rather than a mutational shift from CCR5
- Mechanisms of failure to CCR5 inhibitors is not explained by mutation in the V3 loop, cross-resistance between CCR5 inhibitors is likely
- Macaque study shows similar protection from rectal exposure using 2-hour pre- and 24-hour post exposure prophylaxis with tenofovir plus FTC compared to daily regimen
The abstract book from the Workshop is available to download: