Second case of potential HIV eradication

19 October 2018. Related: Conference reports, Cure-related research, BHIVA Autumn 2018.

Simon Collins, HIV i-Base

One of the highlights of the BHIVA Autumn Conference, slipped in as a couple of slides at the end of the meeting, was that the UK might have a second potential case of HIV eradication (although this is one of the presentations is one that is not online).

The case involves an HIV positive man who has undergone successful allogeneic stem cell transplantation from an unrelated donor homozygous for CCR5 delta-32 deletion.

ART was stopped 15 months post transplant following ethics approval and for the subsequent 12 months HIV has been undetectable by all methods including proviral DNA outgrowth and integrated and total HIV DNA in CD4 cells.

Further details will be presented to a future medical conference.

Reference

Gabriel I. Bone marrow transplants. BHIVA Autumn conference, 4-5 October 2018.

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