Clinical outcomes of adult inpatients with COVID-19

Simon Collins, HIV i-Base

This retrospective case study reported clinical outcomes and related risks of 191 patients in two hospitals in Wuhan, of whom 137 were discharged and 54 died in hospital.

These were people who were sick enough to be hospitalised. Baseline risks associated with dying in hospital included older age and serious comorbities and also having d-dimer >1 μg/mL (OR:18·42; 95%CI 2·64–128·55; p=0·0033).

It also reported that median duration of viral shedding was 20 days (IQR: 17 to 24) in survivors, but SARS-CoV-2 was detectable until death in non-survivors. The longest observed duration of viral shedding in survivors was 37 days.

Ref: Zhou F et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The Lancet, 395(10229);1054-1062. (28 March 2020).

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