Potential to use BOTOX for erectile dysfunction

Simon Collins, HIV i-Base

Although it includes limited evidence, this interesting study reported positive outcomes from using BOTOX as a potential treatment for erectile dysfunction.

This was a randomised double-blind placebo-controlled trial randomised 176 participants to single injections of BOTOX (to one of two doses) or to a saline control group.

Improvements were reported in all scores for the BOTOX vs control groups at 3 months, which significantly favoured the higher dose group after 6 months (p <0.01).

Please see the free full text links and accompanying editorial for full details.

References

1. El-Shaer W, Ghanem H, Diab T, Abo-Taleb A, Kandeel W. Intra-cavernous injection of BOTOX (50 and 100 Units) for treatment of vasculogenic erectile dysfunction: Randomized controlled trial. Andrology. 2021 Jul;9(4):1166-1175. doi: 10.1111/andr.13010.
   https://pubmed.ncbi.nlm.nih.gov/33784020
2. Barros RB. Editorial Comment: Intra-cavernous injection of BOTOX (50 and 100 Units) for treatment of vasculogenic erectile dysfunction: Randomized controlled trial. Int Braz J Urol. 2022 Nov-Dec;48(6):990-991. doi: 10.1590/S1677-5538.IBJU.2022.06.03. PMID: 36173411.
   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747022