Online medical resources
2 June 2004. Related: On the web.
HIV inSite Knowledge Base
New or updated chapters from April and May include:
Clinical overview of HIV disease
http://hivinsite.ucsf.edu/InSite?page=kb-03-01-01
Genotypic testing for HIV-1 drug resistance
http://hivinsite.ucsf.edu/InSite?page=kb-03-02-07
Non-antiretroviral medication-related adverse events during treatment of HIV-related infections and complications
http://hivinsite.ucsf.edu/InSite?page=kb-03-01-07
Adverse events of antiretroviral drugs
http://hivinsite.ucsf.edu/InSite?page=ar-05-01
Dosing of antiretroviral drugs in renal insufficiency and hemodialysis
http://hivinsite.ucsf.edu/InSite?page=md-rr-18
thebody.com
Five people, five treatment interruptions, five outcomes
http://www.thebody.com/confs/retro2004/sti_cme_studies.html?m46h
We can read research about experimental HIV treatment strategies until our eyes glaze over, but sometimes it’s more interesting — and more educational — to hear a doctor talk about some of the patients who have actually taken part in them. Dr. Gerald Pierone brings us in for a closer look at five people who took doctor-guided HIV structured treatment interruptions under a variety of circumstances.
JournalView: a new way to keep up with the latest in HIV medicine
http://www.thebody.com/redirect/journalview/april04.html?m46h
The Body Pro, The Body’s sister site for HIV healthcare professionals, has launched JournalView, a new, monthly analysis of HIV research authored by an HIV physician. Every month, JournalView will scour top medical journals and other publications, selecting key findings and providing expert commentary on their importance to the world of HIV medicine. Click on the link above to read JournalView’s inaugural issue!
Pharmacokinetic Factors In HIV Therapy
An online programme reviewing key issues in HIV pharmacology, and the role of pharmacokinetic factors in the outcomes of antiretroviral therapy. Site requires on-time free registration.
http://clinicaloptions.com/pk0510
Pharmacokinetic and pharmacodynamic principles: a guide for HIV healthcare professionals
Key pharmacokinetic and pharmacodynamic parameters; Characteristics of drug concentrations at steady state, and impact of different dosing regimens; Relationship between antiretroviral concentrations and treatment outcomes.
Factors associated with pharmacokinetic variability in HIV-infected patients
Clinical relevance of interpatient variability in drug concentrations; Factors contributing to PK variability in HIV-infected patients; PK variations associated with demographics, hepatitis and renal disease, pregnancy, and pediatrics.
Integrating pharmacokinetics into treatment decisions: strategies for optimal patient care
PK parameters that may predict clinical outcomes; Advantages and disadvantages of various boosted-PI regimens; Recently observed drug-drug interactions between antiretroviral agents.
Interactive guide to antiretroviral dosing
Interactive tool to access information on dose adjustments recommended for FDA-approved antiretrovirals in specific clinical scenarios (eg, hepatic or renal insufficiency; pediatrics; body weight).