December 2002

Contents

Meeting report

• Protecting mothers from mono and dual therapies, and considering the value of Caesarean sections

Antiretrovirals

• Boosted PIs: differences emerging in efficacy, tolerability, lipids

• Europe steps in to protect discounted drugs for developing countries

• Hair analysis may help determine drug levels, adherence and virological response

• Disadvantage from prior nucleoside therapy persists for years during HAART

Treatment access

• Europe steps in to protect discounted drugs for developing countries

Side effects

• Perspectives on hormonal, mitochondrial and metabolic changes

• IAS panel issues first guidelines for HIV and HIV drug-related metabolic complications (2002)

• Side effects are a common cause of intentional non adherence to HAART

Coinfections and complications

• PML-associated immune restoration disease associated with mortality

Basic science and immunology

• Animal retroviral infections suggest third kind of potential treatment: HIV harm reduction

• Memory T cells do not recognise circulating HIV in late infection

Other news

• Chiron halts major IL-2 study, for business reasons

• EU increases powers, and speeds up actions, of the European medicines agency

• Zinc treatment for diarrhoea reduces child deaths

On the web

• Post-meeting coverage of the 42nd ICAAC

• AIDS-related malignancies in the era of HAART

• Screening for and treatment of anal intraepithelial neoplasia

• Coping with lipodystrophy’s emotional toll

• Beyond HAART: a closer look at immune therapies

• Digging deeper at the resistance workshop

• Medscape conference coverage

• Anaemia, neutropenia, and thrombocytopenia: pathogenesis and evolving treatment options in HIV-infected patients

• Comprehensive health care for people infected with HIV in developing countries BMJ 2002;325:954-957

• Anti-R7V antibodies may protect some HIV-infected patients from developing AIDS: a conversation with Jean-Claude Chermann

• Combining saquinavir with lopinavir/ritonavir?

• Glossary of HIV/AIDS-Related Terms, 4th ed

• HIV and Its Treatment: What You Should Know, 2nd edition

PDFs

• Volume 3 Number 10 December 2002 PDF