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HTB

1 December 2007

Contents

Conference reports

  • Drug interaction studies presented at EACS

Antiretrovirals

  • Half-dose Kaletra tablet approved for paediatric use in the US

Treatment access

  • HIV and TB co-infection and treatment charges in the UK

Pregnancy

  • US updates guidelines on use of ARVs during pregnancy (Dec 2007)
  • Perinatal transmission of HIV in England 2002-2005
  • Risk factors for in utero or intrapartum mother-to-child transmission in Thailand

PK and drug interactions

  • New drug interaction summary tables: maraviroc, integrase inhibitors, etravirine, hormonal contraceptives
  • Acid reducing agents and protese inhibitors
  • Atazanavir, with or without ritonavir, may increase buprenorphine and buprenorphine metabolites, requiring dose adjustment
  • T-20 increases tipranavir levels but not hepatotoxicity
  • The effect of lopinavir/r on the renal clearance of tenofovir

Guidelines

  • US adult treatment guidelines updated (December 2007)

Side effects

  • Case report of efavirenz-associated nephrolithiasis
  • Yellow card reporting scheme for doctors and patients in the UK

Vaccines and microbicides

  • Merck HIV vaccine trial is unblinded

Other news

  • IAS statement on US policy for HIV-positive visitors

On the web

  • PLoS Medicine articles
  • HIV/TB co-infection: meeting the challenge

PDFs

  • Volume 8 Number 11/12 November/December 2007 PDF
  • HTB RSS

Early access

  • Chronic kidney disease (CKD) in HIV positive people linked to time with low CD4 count: partly reversible after effective ART 1 March 2021
  • All early access reports

Current issues

  • March 2021
  • February 2021
  • January 2021
  • Back issues

Special report

  • Early results report 90% efficacy with from Pfizer/BioNTech COVID vaccine 11 November 2020

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