HTB homepage • Conference reports • Articles by subject • Subscribe February 2008 Contents Editorial Volume 9 Number 1/2 January/February 2008 Special reports CROI 2008 – 12 key areas of research: non-technical summary of 25 studies and presentations Conference reports 15th Conference on Retroviruses and Opportunistic Infections, 2-6 February 2008, Boston Increased risk of myocardial infarction associated with abacavir and ddI Position statement by the D:A:D steering committee 3rd International Workshop on Targeting HIV Entry, 7-9 December 2007, Washington DC CXCR4-using HIV found in 8.5% during early HIV infection Background drugs and low maraviroc levels explain resistance in Motivate studies 38th World Conference on Lung Health of the Union Against TB and Lung Disease, December 2007, Cape Town Treatment outcomes in patients who received rifampicin with nevirapine or efavirenz Antiretrovirals Boehringer fails to register tipranavir in Brazil after using Brazilian patients in registrational study Raltegravir approved in Europe and available in the UK Paediatric lopinavir/r receives positive opinion from EMEA Etravirine (TMC-125) approved in the US Changes to atazanavir product label in US HIV-positive adults with CD4 >500 cells/mm3 have similar mortality rates as the general population after seven years ARV treatment Pregnancy Atazanavir exposure in pregnancy Two-dose versus monthly intermittent preventive treatment of malaria with sulfadoxine-pyrimethamine in HIV-positive pregnant women Paediatric care Predictors of mortality in untreated HIV-positive children Pharmacokinetics of lopinavir/ritonavir in infants less than 12 months of age PK and drug interactions Darunavir/ritonavir interaction with clarithromycin warrants caution Updated and new resources on HIV drug interactions Guidelines US treatment guidelines updated (2008) Hepatitis coinfection Comparative study of pegylated interferon formulations in HCV monotherapy Basic science and immunology Probing HIV dependence on host proteins An eye on the benign: pathogenesis lessons from non-pathogenic SIV infections HIV awakens retroviral zombies from cellular slumber Immune activation correlates with CD4 T cell declines in HIV controllers Drug resistance Dual-class mutations affection RTI and NNRTI may be common in experienced patients On the web 58th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) Targeting HIV Entry: 3rd International Workshop PLoS Medicine Breakthroughs in immunology Multiple roles of CCR5 in infectious diseases New resources from HIV inSite New advocacy site: HIV and pregnancy PDFs Volume 9 Number 1/2 January/February 2008 PDF CROI 2008: 12 key areas of research – non-technical summary of 25 studies and presentations HTB homepage • Conference reports • Articles by subject • Subscribe