21 February 2010

Contents

Conference reports

• 12th European AIDS Society Conference (EACS), 11-14 November 2009, Cologne

• Screening for anal cancer recommended for HIV positive men

• Once-daily darunavir/r monotherapy is suboptimal as initial regimen in treatment-naive people

• Central fat accumulation remains a significant problem in patients starting HAART after 2005 with higher incidence in women compared to men

• Alendronate improves bone mineral density in HIV positive people with osteoporosis at 96 weeks

• TMC278 did not show teratogenic potential in animal models

• Etravirine pregnancy data from five cases: no dose adjustment required

• No clinically relevant interactions between TMC278 and oral contraceptives (norethindrone plus ethinylestradiol)

• Gender-based differences in patients receiving antiretroviral therapy

• Pilot PK study of two generic paediatric formulations of lopinavir/ritonavir vs originator products

• Other selected PK and drug interaction summaries from EACS