October 2023

Contents

Editorial

• HTB October/November 2023

• Non-technical summary of articles in HTB October 2023

• Uganda report: Increase in LGBTQI+ assaults and human rights violations need urgent activist responses

Conference reports

• 12th IAS Conference on HIV Science (IAS 2023): further reports

• IAS 2023: Lenacapavir studies at IAS: weekly oral dosing and baseline sensitivity in non-clade B settings

• IAS 2023: LA-CAB/RPV as first-line ART and implementation studies

• IAS 2023: bNAbs for prevention and cure: antiviral and vaccine-like responses

• IAS 2023: High rates of re-suppression with dolutegravir in the ADVANCE study

• IAS 2023: Bictegravir use in pregnancy: more data needed

• IAS 2023: In-utero tenofovir-based PrEP has no effect on children’s bone mineral density

Side effects

• UK surveys on access to New-Fill for facial lipoatrophy

• >10% weight gain during first two years of ART linked to double the risk of cardiometabolic disease

• Altered kidney function associated with alcohol and cannabis use by women living with HIV

HIV prevention and transmission

• EU approves cabotegravir as injectable PrEP

• Mutations associated with resistance to dapivirine vaginal ring: reported in 7/38 women seroconverting in the open-label HOPE study

Vaccines and microbicides

• Early phase 1 HIV vaccine study launched in the US and South Africa

PDFs

• HTB: no. 10/11 (Oct/Nov 2023) PDF download