December 2023

Contents

Editorial

• HTB December 2023/January 2024

• i-Base 2024 appeal: support for LGBTQI+ refugees in Kakuma

Special reports

• Latest figures published on HIV in the UK: 2023 report

Conference reports

• 14th International Workshop on HIV and Ageing

• Sarcopenia and mitochondrial dysfunction in people living with HIV: the impact of ageing

• Measuring sarcopenia in people living with HIV

• 19th EACS (EACS 2023)

• EACS 2023: HIV cure-related research

• EACS 2023: European guidelines fully revised (October 2023)

• EACS 2023: Prevalence of doravirine drug resistance in large cohort in British Columbia

• EACS 2023: Switching to daily fixed-dose doravirine/islatravir: 96-week results

• EACS 2023: TDF/FTC dual-nuke ART: not supported by ALTAR study

• EACS 2023: EATG video campaign against HIV stigma

Antiretrovirals

• First-line ART drops below US $45 a year for low-income countries

• Potential for monthly injectable: nanoformulated tenofovir/3TC/dolutegravir

Treatment strategies

• Dolutegravir monotherapy still not recommended: 4-year follow up in early-treated durably suppressed participants

• CD4:CD8 ratio recovery reduces with higher age when starting ART

Treatment access

• CHAI 2023 market report: decline in HIV funding threatens 20 years of progress

Women's health

• Modest increase in rate of cardiovascular disease progression during perimenopause for women living with HIV

Paediatric care

• Review of US PEPFAR programme highlights continued higher infant mortality

PK and drug interactions

• Oral tenofovir/FTC increases clearance of bNAb VRC01: implications for future research

Guidelines

• HIV guidelines recommend a statin for all people older than 40: new BHIVA document

mpox

• Mpox update: recent publications (2023)

• Mpox vaccines still available and recommended in the UK and US

Book and film reviews

• Our Stories Told By Us: Celebrating the African contribution to the UK HIV response

Other news

• Pricing new gene therapies for sickle-cell: implications for an HIV cure

• Up to 3% of medical research papers are fake

PDFs

• HTB no 12 December 20023 / January2024